Zuckerkandl's tubercle is a pyramidal extension of the thyroid gland, present at the most posterior side of each lobe^[1][2]. Emil Zuckerkandl described it in 1902 as the processus posterior glandulae thyroideae. Although the structure is named after Zuckerkandl, it was discovered first by Otto Madelung in 1867 as the posterior horn of the thyroid. The structure is important in thyroid surgery as it is closely related to the recurrent laryngeal nerve, the inferior thyroid artery, Berry's ligament and the parathyroid glands. The structure is subject to an important amount of anatomic variation , and therefore a size classification is proposed by Pelizzo et al.

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v • d • e Human anatomy, endocrine system: endocrine glands (TA A11, GA 11.1269) Islets of pancreas Alpha cell · Beta cell · Delta cell · PP cell · Epsilon cell Hypothalamic/ pituitary axes +parathyroid Pituitary Posterior pituitary Pars nervosa · Median eminence · Infundibular stalk Pituicyte · Herring bodies Anterior pituitary Pars intermedia · Pars tuberalis · Pars distalis Acidophils (Somatotropes, Lactotropes) · Basophils (Corticotropes, Gonadotropes, Thyrotropes) · Chromophobe Thyroid axis Thyroid gland Thyroid isthmus · Lobes of thyroid gland · Pyramidal lobe of thyroid gland · Zuckerkandl's tubercle Parafollicular cell · Thyroid epithelial cell Parathyroid gland Oxyphil cell · Chief cell Adrenal axis: Adrenal gland Cortex Zona glomerulosa · Zona fasciculata · Zona reticularis Medulla Chromaffin cells Paraganglia Organ of Zuckerkandl Gonadal axis Gonad: Testes · Ovaries · Corpus luteum Pineal gland Pinealocyte · Corpora arenacea endocrine navs: anat/physio/dev/hormones, noncongen/congen/neoplasia, symptoms+signs/eponymous, proc