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William T. Summerlin is a dermatologist who, as a medical researcher, perpetrated a notorious scientific fraud.

In 1974 Summerlin worked under immunologist Robert A. Good at the Memorial Sloan-Kettering Cancer Center in New York City, conducting research in transplantation immunology. He claimed that he could transplant tissue from unrelated animals by keeping the tissue in culture for four to six weeks. He used white mice with patches of black fur which he had colored with a black permanent marker.

In 1974, Summerlin was discovered when he made a presentation to Dr. Good; lab assistants noticed that the patches had been drawn on the mice and could be removed using alcohol.

Summerlin later attributed his deceptive behavior to a combination of mental and physical exhaustion, a heavy clinical and experimental workload, and pressure to publicize positive results.[1] Memorial Sloan-Kettering president Dr. Lewis Thomas said that Dr. Summerlin was suffering from a "serious emotional disturbance."[2] After the incident, Summerlin reportedly moved to rural Louisiana to practice medicine.[3]

As a result of the Summerlin incident, the term "painting the mice" has become a synonym for research fraud.[4] Author Joseph Hixson wrote a book about the scandal entitled The Patchwork Mouse.[5]

[edit] References

  1. ^ The Evolution of the "Scientific Misconduct" Issue: An Historical Overview by Marcel C. LaFollette, Proceedings of the Society for Experimental Biology and Medicine 224:211-215 (2000)
  2. ^ The S.K.I. Affair (Contd.), Time magazine, June 3, 1974
  3. ^ Where are they now?, by Paroma Basu. Nature Medicine 12, 492 - 493 (2006). Published online: 27 April 2006
  4. ^ Truth and Trustworthiness in Research, by Caroline Whitbeck, Online Ethics Center at the National Academy of Engineering
  5. ^ Skin Deep, review of The Patchwork Mouse, Time magazine, March 8, 1976

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