William Standish Knowles Information & William Standish Knowles Links at HealthHaven.com

**William Standish Knowles**
William Standish Knowles
	;
Born	June 1, 1917 (age 92); Taunton, Massachusetts, USA
Nationality	United States
Fields	Chemistry
Institutions	Thomas and Hochwalt Laboratories; Monsanto Company
Alma mater	Columbia University
Doctoral advisor	Robert Elderfield
Known for	Chiral phosphine ligands that proved effective in the enantioselective synthesis of L-DOPA
Notable awards	Nobel Prize in Chemistry (2001)

William S. Knowles (born June 1, 1917) is an American chemist. He was born in Taunton, Massachusetts.

He shared the Nobel Prize in Chemistry in 2001 with Ryoji Noyori and K. Barry Sharpless for the development of catalytic asymmetric synthesis, which is a technology relevant to the preparation of many pharmaceuticals. Knowles led a team of researchers that developed chiral phosphine ligands that proved effective in the enantioselective synthesis of L-DOPA.^[1]^[2] Knowles conducted this prize-winning research at Monsanto Company.

He currently resides in St. Louis, Missouri.

[edit] References

^ Vineyard, B. D.; Knowles, W. S.; Sabacky, M. J.; Bachman, G. L.; Weinkauff, D. J. (1977). "Asymmetric Hydrogenation. Rhodium Chiral Bisphosphine Catalyst". Journal of the American Chemical Society 99 (18): 5946–5952. doi:10.1021/ja00460a018.
^ Knowles, W. S. (2002). "Asymmetric Hydrogenations (Nobel Lecture)". Angewandte Chemie International Edition 41: 1998–2007. doi:10.1002/1521-3773(20020617)41:12<1998::AID-ANIE1998>3.0.CO;2-8.

[edit] External links

Knowles's Nobel Foundation biography
Knowles's Nobel Lecture Asymmetric Hydrogenations

[0] Vineyard, B. D.; Knowles, W. S.; Sabacky, M. J.; Bachman, G. L.; Weinkauff, D. J. (1977). "Asymmetric Hydrogenation. Rhodium Chiral Bisphosphine Catalyst". Journal of the American Chemical Society 99 (18): 5946–5952. doi:10.1021/ja00460a018.

[1] Knowles, W. S. (2002). "Asymmetric Hydrogenations (Nobel Lecture)". Angewandte Chemie International Edition 41: 1998–2007. doi:10.1002/1521-3773(20020617)41:12<1998::AID-ANIE1998>3.0.CO;2-8.

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