| advertise add site services publishers database health videos | ![]() | about toolbar stats live show health store more stuff JOIN/LOGIN |
Endothelial cells enhance tumor cell invasion through a crosstalk... caliperls.com | Talking Watch, Talking Watches, Talking Clock, Talking Bible, Talking... independentliving.com | Cell Biology of Signaling Complexes in Phototransduction researchresources.bumc.bu... | - Translational Approaches to Cell Signaling in Shock and... cimit.net |
[edit] Wikipedia Day AwardsHello, all. It was initially my hope to try to have this done as part of Esperanza's proposal for an appreciation week to end on Wikipedia Day, January 15. However, several people have once again proposed the entirety of Esperanza for deletion, so that might not work. It was the intention of the Appreciation Week proposal to set aside a given time when the various individuals who have made significant, valuable contributions to the encyclopedia would be recognized and honored. I believe that, with some effort, this could still be done. My proposal is to, with luck, try to organize the various WikiProjects and other entities of wikipedia to take part in a larger celebrartion of its contributors to take place in January, probably beginning January 15, 2007. I have created yet another new subpage for myself (a weakness of mine, I'm afraid) at User talk:Badbilltucker/Appreciation Week where I would greatly appreciate any indications from the members of this project as to whether and how they might be willing and/or able to assist in recognizing the contributions of our editors. Thank you for your attention. Badbilltucker 17:03, 30 December 2006 (UTC) [edit] RecruitmentRecruiting editors to make up for attrition is a constant task. According to Wikipedia:WikiProject Council/Guide/WikiProject, the most effective methods is through the use of the project banner template. The guide suggests that these go on the Talk Pages of articles, and not on the article main page. Additional recruitment tactics include trawling through Molecular Biology Projects and finding participants who list signaling as an interest of theirs, and inviting them directly. Similarly, users who list signaling as an interest on the user page. Tip for finding these: go to signal transduction or cell signaling and click on What Links Here - look for User Pages and Project Pages, etc. Biochemza, 12:12, 3 November 2007 (UTC) [edit] Willing to HelpHi, I noticed an invitation to help on this project from some edit I had done on another page and so I wandered here and I'm willing to help, if you can use me (also, didn't mean to put up a big "new discussion" headline for this comment, but I didn't know where else to put it). Unfortunately I'm relatively new to the Wikipedia community, so I'm not really sure how to help. I currently work in a signaling laboratory that focuses on nutrient signalling to the mTOR-S6 Kinase pathway. We do mostly in-vitro studies and have recently been interested in transcriptional regulation by the pathway. I think this project is a great idea. I also think that the best way to organize it would be through diagrams, i.e. clickable diagrams akin to how Cell Signaling does it, although I understand that this would be extremely complicated. Best, Mhsia 18:17, 3 August 2006 (UTC) Bravo guys. Wish I could help. How to depict information seems a point of interest. Hmmm, maybe I'll have something to say after boning up on it a bit. There is often a trade off between clarity and density, but a good 'architecture' can allow both. One problem seems to occur when one item has several different 'meanings' or functions. Perhaps some help from other communities, like logic, graphics, programmers, who?. How about Flash that splits/merges to show alternatives? Wblakesx 23:46, 18 October 2006 (UTC)wblakesx [edit] Anybody still here?Hi guy's you are doing a great job on the Hh pathway. I would be happy to help if you need any ideas or questions. I have helped create http://hedgehog.sfsu.edu I have done most of creation along with reading almost every article that has come out on the Hh pathway. The site is a little outdated due to the PI being very ill and funding for the project has decreased. However, I would really like to help you guys out on wikipedia if needed. Warmest regards, email me at drew007martin@gmail.com
[edit] Project ManagementThis section deals with management of the actual project itself, such as the creation of templates, task forces, etc. [edit] Projects within this WikiProjectAnyone who works in the cell signaling field knows its a huge, messy, poorly understood field. I think we should break this WikiProject down into more manageable projects, grouped by broad subject area. I am quite specialised in my particular field, so I wouldn't really be able to create a list of these mini-projects, but I think if we added projects according to our specialisation, it would eventually flesh out into a nice list, by itself. For example, I would add something like Tyrosine kinase signaling to the Projects section, and then that mini-project would obviously focus on tyrosine kinases. At a later stage, it might even be further subdivided (Receptor PTKs vs Non-receptor PTKs or whatever) - as the workload calls for it. Any comments? Biochemza, 02:25, 3 November 2007 (UTC) [edit] Task ForcesAs this project grows, it might be handy to form task forces to focus on specific things. Like fixing Categorisation, or whatever. See Wikipedia:WikiProject_Council/Guide/Task_forces. Discussions? Biochemza, 11:33, 3 November 2007 (UTC) [edit] Templates[edit] Existing TemplatesHey nice work on the templates, i'll start adding them to the appropriate articles and start expanding their content, one by one. Rockpocket 23:50, 6 June 2006 (UTC) [edit] Project BannerI have recently created a banner for Wikipedia:WikiProject Biology which has assessment parameters. I notice that your existing banner does not. Given the amount of overlap in the biology sector, and the concerns expressed elsewhere about the proliferation of project banners, I was wondering whether the members of this project would be interested in perhaps utilizing the Biology banner, with a "drop down tab" for this project, perhaps similar to the {{WPMILHIST}} banner. Doing so would permit for individual assessment for each project, as that is something the Military History banner does, while at the same time reducing the amount of banner "clutter" on talk pages. If you would be interested in such an arrangement, please let me know and I will work to revise the Biology banner to include the "drop-down" tab and make the other arrangements required for your project, as well as theirs, to have assessment data available. Thank you. John Carter 20:56, 27 April 2007 (UTC)
I think the templates used on these other pages might also be useful guidelines/starting points:
[edit]I think the lipid signaling navbox should be expanded to include many of the enzymes/substrates/products in Lipid_signaling. Biochemza, 20:10, 5 November 2007 (UTC) [edit] Template Requests[edit] UserBoxCan someone create a userbox along the lines of "This user is a member of this project". Biochemza, 15:58, 2 November 2007 (UTC) [edit] Welcome TemplateA Welcome template new participants. See Welcome Wagon. Biochemza, [edit] Project directoryHello. The WikiProject Council has recently updated the Wikipedia:WikiProject Council/Directory. This new directory includes a variety of categories and subcategories which will, with luck, potentially draw new members to the projects who are interested in those specific subjects. Please review the directory and make any changes to the entries for your project that you see fit. There is also a directory of portals, at User:B2T2/Portal, listing all the existing portals. Feel free to add any of them to the portals or comments section of your entries in the directory. The three columns regarding assessment, peer review, and collaboration are included in the directory for both the use of the projects themselves and for that of others. Having such departments will allow a project to more quickly and easily identify its most important articles and its articles in greatest need of improvement. If you have not already done so, please consider whether your project would benefit from having departments which deal in these matters. It is my hope that all the changes to the directory can be finished by the first of next month. Please feel free to make any changes you see fit to the entries for your project before then. If you should have any questions regarding this matter, please do not hesitate to contact me. Thank you. B2T2 23:35, 25 October 2006 (UTC) [edit] Welcome WagonI think we should have a welcome wagon. Nothing quite as formal as a welcoming committee (because, frankly, that seems like too much hard work), but if participants are checking this project and notice someone new signed up, it would be nice to drop them a line on their Talk page to say hello and welcome. Creating a Project-specific Welcome template might be the way to go? Biochemza, 21:11, 3 November 2007 (UTC) [edit] General Topic Discussions[edit] Cell Signaling Diagramscheck out Burke's Reconnections and the Visual Thesaurus.Wblakesx 22:52, 19 November 2006 (UTC)wblakesx JWSchmidt and I were talking about adding in signaling diagrams on the relevant protein pages. One thing I thing would be useful would be if the diagrams were actually hyper-linked, such that you could click from the protein name in the figure to the relevant article. There are complications, obviously, to the idea of having such diagrams: 1) Some proteins, like Akt for example, link into multipe signaling pathways 2) Not everyone agrees on all the signaling points 3) Some signaling interactions are tissue specific. 4) Some signaling interactions are cell-stage specific (for example there are differences in signaling between the proliferation-competent cell and the cell once it is differentiated into a particular tissue-type and becomes post-mitotic). But even with these problems, it seems that giving the signaling context to every protein that participates in signaling pathways would be extremely useful. This would require coordinating with the large "Protein" project and their templates as well... and would require a section for every protein that is in a signaling pathway as to its role in that pathway. Just some suggestions...
Gacggt 12:03, 19 June 2006 (UTC) Okay, this is what I think the main ideas/questions are:
Peter Z.Talk 19:19, 19 June 2006 (UTC) one last question...
Gacggt 20:40, 19 June 2006 (UTC)
Peter Z.Talk mentioned that he would incorporate the scheme used in my diagrams for the TGF beta signaling pathway, which he did in the JAK-STAT signaling pathway. I created a page in I moved the page the proposed page to Wikipedia:WikiProject Molecular and Cellular Biology/Diagram guide. Feel free to take a look and make any changes, additions, or discuss the scheme. --GAThrawn22 19:25, 8 July 2006 (UTC) [edit] Article structureI am not sure that a single sucture for signaling pathway articles is going to work. Pathways are pretty abstract concepts and exist only as a biologist's way of organising their research... PS Otherwise I think this project is a good idea. A lot of quite important (I would think) articles on this subject are in a really sad state. I'll try to encourage more people to participate. The Meaning of Liff 20:18, 6 June 2006 (UTC) [edit] Pathway namesWhat do you think of these names? (source)
--JWSchmidt 03:30, 25 June 2006 (UTC)
[edit] Notable labsI propose to add links to most notable labs working on a particular pathway in external links sections of articles. It is too much to hope that the articles will always be maintained up to date. It could help students and researchers new to the subject get up to speed on the latest developments. As this could become a vehicle of shameless self promotion, we need strict criteria for inclusion. Generally, the lab must be accepted among the majority of researchers in the subject area as influential, but this is near impossible to verify. I suggest these rules:
--Peter Z.Talk 20:21, 26 June 2006 (UTC) Hi... actually I think this is too much of a judgement call. It seems fine to list references, and to point to seminal papers - but annointing a sub-set of signaling labs as the most important seems fraught with problems. Just my opinion. Also, one would point to different labs for different contexts, even in the same pathway. Sorry but I strongly disagree with this idea. Gacggt 20:28, 26 June 2006 (UTC)
[edit] CategoriesI have just realised that we have both Category:Signal transduction and Category:Cell signaling. Now, we do need separate articles for these terms, but I don't think separate categories are justified. I suggest to move all articles to Cell signaling and get rid of signal transduction. I am not sure how category mechanics/bureaucracy works, need to look it up. It is also about time we agreed on a category system. I suggest we create these subcategories in Category:Cell signaling: Signaling pathways, Ligands (alternatively Cell signaling ligands), Receptors (alternatively Cell signaling receptors), Kinases, Transcription factors. Articles relevant to a particular pathway could be linked together using navboxes, modelled after TGF_beta_signaling_pathway#Summary_table. If there are no objections, I'll proceed to sort things out. It's the best I can do until I get full text access to journals and can get back to writing. Peter Z.Talk 13:28, 8 July 2006 (UTC) I agree. --GAThrawn22 19:17, 8 July 2006 (UTC)
Great idea! Biochemza, 13:30, 2 November 2007 (UTC) [edit] Sub categoriesI have created the following sub-categories in (or moved them to sub-categories of) Category:Cell signaling:
Biochemza, 18:13, 2 November 2007 (UTC)
[edit] Category renaming/merging/deletionsI propose that Category:Tyrosine kinase receptors be renamed to Category:Receptor tyrosine kinases. The first term implies that tyrosine kinases are ligands that bind to specific receptors, whereas the term actually means receptors that have a tyrosine kinase motif on the cytosolic domain, or discrete, soluble tyrosine kinases conformationally bound to the receptor cytosolic domain. I could be wrong though (I haven't actually clicked through and read all the articles linking to that category - who knows, maybe I would have learned something). What thoughts/disagreements/comments? Biochemza, 03:28, 3 November 2007 (UTC) [edit] PortalI think it would be really great to have a Cell Signaling Portal. Check out these featured Portals: Biochemza, 11:52, 3 November 2007 (UTC) [edit] Specific Article/Topic Requests for Help[edit] CholesterolWhoa!!! Adding choleseterol as a postranslation modification (what's the name of it - cholesteroylation or something? Do we have an article about this?) with roles in protein trafic and cell signaling?!? We thought we know everething about the ol' membrane fella - it's been researched for some half a century, at least. Why doesn't SHH-N stay anchored to the plasma membrane the way the mirystoylated proteins are (cholesterol in fully extended state is as long as myristate if not longer) but instead leaves the cell, does DISP have anything to do with it? Why is the presence of cholesterol moiety so important for the receptor/ligand recogntion? What would happen if the cholesterol moiety is cleaved off SHH-N outside the cell in a regulated manner? Would the reduction of cholesterol content inside the cells due to cholesterol lowering diets affect somehow these processes? Are there any drugs outthere that inhibit any of the cholesterol-dependent events - cholesterol attachment, excretion and PTCH binding? Sorry, i couldn't help it, i read this new stuff and my head started spinning around. -- Boris 03:25, 19 June 2006 (UTC)
[edit] Regarding KisspeptinWould anyone like to help me make a page for the GnRH regulating protein kisspeptin. There isn't one on Wikipedia yet.--JE.at.UWOU|T 18:35, 14 November 2006 (UTC) [edit] PAC-1Cross-posted at Wikipedia talk:WikiProject Molecular and Cellular Biology. An editor has raised awareness to PAC-1 on WP:DRUGS. I thought some project contributors may have heard of it/be interested in contributing to the article. Thanks, Fvasconcellos 16:46, 26 December 2006 (UTC) [edit] Changes to the WP:1.0 assessment schemeAs you may have heard, we at the Wikipedia 1.0 Editorial Team recently made some changes to the assessment scale, including the addition of a new level. The new description is available at WP:ASSESS.
Each WikiProject should already have a new C-Class category at Category:C-Class_articles. If your project elects not to use the new level, you can simply delete your WikiProject's C-Class category and clarify any amendments on your project's assessment/discussion pages. The bot is already finding and listing C-Class articles. Please leave a message with us if you have any queries regarding the introduction of the revised scheme. This scheme should allow the team to start producing offline selections for your project and the wider community within the next year. Thanks for using the Wikipedia 1.0 scheme! For the 1.0 Editorial Team, §hepBot (Disable) 22:10, 4 July 2008 (UTC) [edit] Wikipedia 0.7 articles have been selected for Cell signalingWikipedia 0.7 is a collection of English Wikipedia articles due to be released on DVD, and available for free download, later this year. The Wikipedia:Version 1.0 Editorial Team has made an automated selection of articles for Version 0.7. We would like to ask you to review the articles selected from this project. These were chosen from the articles with this project's talk page tag, based on the rated importance and quality. If there are any specific articles that should be removed, please let us know at Wikipedia talk:Version 0.7. You can also nominate additional articles for release, following the procedure at Wikipedia:Release Version Nominations. A list of selected articles with cleanup tags, sorted by project, is available. The list is automatically updated each hour when it is loaded. Please try to fix any urgent problems in the selected articles. A team of copyeditors has agreed to help with copyediting requests, although you should try to fix simple issues on your own if possible. We would also appreciate your help in identifying the version of each article that you think we should use, to help avoid vandalism or POV issues. These versions can be recorded at this project's subpage of User:SelectionBot/0.7. We are planning to release the selection for the holiday season, so we ask you to select the revisions before October 20. At that time, we will use an automatic process to identify which version of each article to release, if no version has been manually selected. Thanks! For the Wikipedia 1.0 Editorial team, SelectionBot 23:17, 15 September 2008 (UTC) [edit] Coordinators' working groupHi! I'd like to draw your attention to the new WikiProject coordinators' working group, an effort to bring both official and unofficial WikiProject coordinators together so that the projects can more easily develop consensus and collaborate. This group has been created after discussion regarding possible changes to the A-Class review system, and that may be one of the first things discussed by interested coordinators. All designated project coordinators are invited to join this working group. If your project hasn't formally designated any editors as coordinators, but you are someone who regularly deals with coordination tasks in the project, please feel free to join as well. — Delievered by §hepBot (Disable) on behalf of the WikiProject coordinators' working group at 05:04, 28 February 2009 (UTC) [edit] Article alertsThis is a notice to let you know about Article alerts, a fully-automated subscription-based news delivery system designed to notify WikiProjects and Taskforces when articles are entering Articles for deletion, Requests for comment, Peer review and other workflows (full list). The reports are updated on a daily basis, and provide brief summaries of what happened, with relevant links to discussion or results when possible. A certain degree of customization is available; WikiProjects and Taskforces can choose which workflows to include, have individual reports generated for each workflow, have deletion discussion transcluded on the reports, and so on. An example of a customized report can be found here. If you are already subscribed to Article Alerts, it is now easier to report bugs and request new features. We are also in the process of implementing a "news system", which would let projects know about ongoing discussions on a wikipedia-wide level, and other things of interest. The developers also note that some subscribing WikiProjects and Taskforces use the Message sent by User:Addbot to all active wiki projects per request, Comments on the message and bot are welcome here. Thanks. — Headbomb {ταλκκοντριβς – WP Physics} 08:56, 15 March, 2009 (UTC) [edit] Merge this with Wikipedia:WikiProject Molecular and Cellular Biology?Was browsing around when I noticed this wikiproject. Am I correct to assume that this wikiproject is not as active as it used to be? Or is there perhaps just not much to discuss on the talk page? Either way I was thinking of stepping up and merging this entire project under the Wikipedia:WikiProject Molecular and Cellular Biology project as a task force? Would anyone have any comments that they would like to bring up? Everything on this page will remain the same, only difference/change would be to merge the wikiproject template talk page tags as one (so the template would look like: {{WPMCB|cell-signaling=yes}}. My hope is that this might increase viewership levels of this particular project for those who might have an incling towards this field of molecular biology (via noticing this page from the MCB project). I shall also post this on the MCB proposal talk page. Cheers. Calaka (talk) 11:08, 5 May 2009 (UTC) [edit] Inter/intracellar signal transductionDoes anyone have any good techniques/suggestions/etc for outlining signal transduction outside or inside a cell without using cartoons/diagrams (i.e. some type of all-text approach)? ---kilbad (talk) 01:33, 11 June 2009 (UTC) |
| ↑ top of page ↑ | about thumbshots |