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Key components of the MAPK/ERK pathway, by JWSchmidt.

Some Wikipedians have formed a project to better organize information in articles related to Cell Signaling. This page and its subpages contain their suggestions; it is hoped that this project will help to focus the efforts of other Wikipedians. If you would like to help, please inquire on the talk page and see the to-do list there.

For more information on WikiProjects, please see Wikipedia:WikiProject and Wikipedia:WikiProject/Best practices.

[edit] Title

WikiProject on Cell Signaling

[edit] Scope

This project is dedicated to improving and organising the Wikipedia articles on cell signaling to provide a convenient and reliable reference of the known signal transduction pathways. It covers the pathway pages and individual protein pages related to them.

[edit] Goals

• Creating comprehensive articles for each known cell signaling pathway
• Organising cell signaling articles with navigation boxes like these: Wikipedia:WikiProject Molecular and Cellular Biology#Protein topics navigation boxes.
• Organising and creating articles on notable proteins involved in signaling pathways.
• Providing each pathway with a clear diagram of its structure.
• Clearly citing sources, especially for active research topics

This section requires expansion.

[edit] Target audience

• Introduction to pathway articles should make minimal use of jargon and be kept relatively simple
• Subsections and protein pages can be more technical

[edit] Parentage

This is a daughter project of WikiProject Molecular and Cellular Biology

[edit] Similar WikiProjects

WikiProject Clinical medicine and WikiProject Drugs may be relevant to this project.

[edit] Guidelines

This section requires expansion.

[edit] Open Tasks

edit · history · watch · refresh  To-do list for Wikipedia:WikiProject Cell Signaling:

Here are some tasks you can do: Requests: Recruit people from MolBiol projects and people who list signaling as an interest on their User pages. (See Recruitment on the Talk Page). Design a convention for drawing pathway diagrams. (See Cell Signaling Diagrams on the Talk Page). Build a sample pathway article: Hedgehog signaling pathway Resolve the Cell signaling/Signal transduction merger, no merge Come to a consensus regarding cell signaling article style. (See Article Structure on the Talk Page). Templates (See Templates on the Talk Page). Create a Talk template for use on Talk Pages. (See Project Banner on the Talk Page). Figure out why this task template isn't working quite as nicely as it should. Create a userbox for this WikiProject. Create more signaling templates. Create more navboxes. (See Wikipedia:Navigational templates) Find existing navboxes and add to the Template section. Categories (See Categories on the Talk Page). Propose Category Merge: Category:Signal Transduction and Category:Cell Signaling Wait for discussion/consensus on category merge. Assess and label/categorise Category:Unassessed_Cell_signaling_articles Wikify: WikiProject banner. Add the WikiProject banner using {{Template:Cell Signaling Project}} to the Talk Page of all applicable articles. This will help with recruiting volunteers as well as categorising articles for easy reference. (See Project Banner on the Talk Page). Add Infoboxes or navboxes where appropriate. Wikify internal links (wiki-links) Improve articles by creating lead paragraphs and/or section headings. If you do not have time to wikify, you can still assist by tagging an article for Wikification. To do this, add {{wikify}} to the top of the article. Merge: Merge Articles: Cell Signaling Networks and Cell Signaling. Verify: Mark articles that need verification by using {{fact}}, {{Unreferencedsection}}, {{refimprove}}, {{unreferenced}}. Cleanup: Mark articles for cleanup using {{cleanup}} Stubs: Propose a new stub: {{cell-signaling-stub}}. Wait for approval of new {{cell-signaling-stub}} (Discussion this stub proposal here. Also - anyone got a nice picture we could use for this stub?) Add {{signaltransduction-stub}} notices to all stubby articles. Make sure main article of all Category:Stub-Class_Cell_signaling_articles have {{signaltransduction-stub}}. It may seem redundant to have a stub template on the main page when the project banner also lists the article as a stub, but some people into de-stubbing don't look at project pages or talk pages - just main article pages to get a list of stubs they can work on. The more ways to recruit people to help, the better. Expand {{signaltransduction-stub}} articles. expand nitrosylation article.

[edit] Departments

• Wikipedia:WikiProject Cell Signaling/Assessment - the assessment department.

[edit] Participants

If you'd like to join the project, please add your name here. If you'd really like to contibute, but don't have much time, you can still participate by adding your name to the Guestlist.

[edit] Guestlist

If you'd really like to contribute, but don't have much time, you can still participate by adding your name to the Guestlist.

[edit] Article Structure

Proposed structure of a pathway article:

• General introduction - keep it simple and clear
• History/Discovery - discovery, seminal papers
• Mechanism - the proteins involved and how they interact.
• Role - the role of the pathway
• Human disease - alternatively this can be incorporated into the previous section
• Current research - recent advances, future directions

For individual proteins, see suggestions in Wikipedia:WikiProject_Molecular_and_Cellular_Biology#Structures

Proposed scheme for pathway diagrams is described here. Please do comment and contribute.

[edit] Hierarchy definition

No classification of this project has been defined.

This section requires expansion.

[edit] Projects

Cell signaling and signal transduction is a very broad field. This section breaks this WikiProject down into smaller, more manageable "mini" projects, with a more specific subject set. Please feel free to add a mini project according to your expertise, or jump in and help on a specific mini project.

• Tyrosine kinase signaling.

This section requires expansion.

[edit] Adopt an article

Similar to the Collaboration of the week, but on a smaller scale, you might want to "adopt" an article. This would involve doing the research, writing, and picture-taking (if possible) for either a non-existent article or a stub. Of course, everyone else can still edit an adopted article, and you can work on other things too, but the idea is to find a focus for a while, to try and build up the number of quality articles the Project has produced.

• Example article: User:Example

[edit] General strategy and discussion forums

• /General
• /Strategy

This section requires expansion.

[edit] Templates

[edit] Infoboxes

To do

[edit] WikiProject Banners

{{Template:Cell Signaling Project|class=???|importance=???}}

WikiProject Cell Signaling		Cell SignalingWikipedia:WikiProject Cell SignalingTemplate:WikiProject Cell SignalingCell signaling articles
v • d • e This article is part of WikiProject Cell Signaling, an attempt to better organise information in articles related to cell signaling and signal transduction. If you would like to participate, you can edit the article attached to this page, or visit the Cell Signaling WikiProject project, where you can join the project and/or contribute to the discussion.  ???  This article has not yet received a rating on the project's quality scale.  ???  This article has not yet received a rating on the project's importance scale.

[edit] Stub Template

{{signaltransduction-stub}}

This signal transduction article is a stub. You can help Wikipedia by expanding it. v • d • e

[edit] NavBoxes

[edit] General

{{Template:Cell_signaling}}

[edit] Specific pathways

{{Template:Lipid_signaling}}

{{Template:TGF beta signaling}}

{{Template:Calcium signaling}}

{{Template:MAP kinase activation}}

[edit] Signaling molecules

{{Template:Signaling proteins}}

{{Template:Cytokines}}

{{Template:Serine/threonine-specific protein kinases}}

{{Template:Kinases}}

{{Template:Tyrosine kinases}}

{{Template:Protein tyrosine phosphatases}}

[edit] Receptors

{{Template:Receptor agonists and antagonists}}

{{Template:T cell receptor}}

{{Template:Growth factor receptors}}

{{Template:Transmembrane receptors}}

{{Template:Tumor necrosis factor receptor superfamily}}

{{Template:Neuropeptide receptors}}

{{Template:G protein-coupled receptors}}

{{Template:Immune receptors}}

{{Template:Chemokine receptors}}

[edit] Other molecules

{{Template:Adaptor proteins}}

{{Template:Neurotrophins}}

[edit] Articles in Categories

• Category:Signal transduction
• Category:Cell signaling (proposed to be merged with Category:Signal Transduction).

[edit] Discussion Archives

• #1

[edit] Tools

[edit] Wikifying Tools

(From Wikipedia:WikiProject_Wikify)

• Can We Link It? - tool for suggesting and adding possible wiki links to articles. Progressively learns what's a good and a bad link. See here for more info. Also checks for unbalanced wiki syntax, which is sometimes a problem when articles are added by new users.
• The Wikipedia Toolbar for the Firefox web-browser can make editing, formatting and linking much more efficient.
• Also useful is the wikification toolbox containing quick links to Wiki guidelines and handy code snippets

[edit] Categorisation tools

(From Wikipedia:WikiProject Categories)

• Category trees – Dumps of the category tree (very handy).
• User:Pearle
• Category Tree and Category Scan

[edit] Sister Project links

Wikimedia Commons has media related to: Cell Signaling Wikiquote has a collection of quotations related to: WikiProject Cell Signaling Look up wikiproject cell signaling in Wiktionary, the free dictionary. Wikinews has related news: Cell Signaling

Wikibooks has more on the topic of WikiProject Cell Signaling Wikisource has original text related to this article: WikiProject Cell Signaling Wikispecies has information related to: Cell Signaling Meta has related information at: Cell Signaling

Find more about Cell Signaling on Wikipedia's sister projects: Definitions from Wiktionary Textbooks from Wikibooks Quotations from Wikiquote Source texts from Wikisource Images and media from Commons News stories from Wikinews Learning resources from Wikiversity