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Leukonychia (or Leuconychia, also known as "White nails" [1]) is a medical term for white discoloration appearing on nails.[2]:658-9 It is derived from the Greek words Leuko white and Onyx nail. The most common cause is injury to the base of the nail (the matrix) where the nail is formed.
[edit] Types of Leukonychia[edit] Leukonychia TotalisThis condition is a whitening of the entire nail. This may be due to hypoalbuminaemia (low albumin), which is caused by the nephrotic syndrome (a form of kidney failure), liver failure, protein malabsorption and protein-losing enteropathies. A genetic condition, and a side effect of sulphonamides, a family of antibiotics can also cause this appearance.[3][4] [edit] Leukonychia PartialisThis condition is whitening of parts of the nail. There are several types of this condition. [edit] Leukonychia Striata or Transverse LeukonychiaAlso called Muehrcke's lines, this is a whitening or discoloration of the nail in bands or "stria". It may be caused by cirrhosis, chemotherapy,[5] or physical injury to the nail matrix. (e.g. excessive nail "tapping" or slamming in a car door).[6][7][8] This condition looks similar to Mee's lines, a condition caused by Arsenic, Lead, or other heavy metal poisoning. [edit] Leukonychia PunctataAlso known as 'True' Leukonychia. This is the most common form of Leukonychia, small white spots on the nails. Picking and biting of the nails are a prominent cause in young children and nail biters. In most cases, when white spots appear on a single or a couple of fingers or toes, the most common cause is injury to the base (matrix) of the nail. When this is the case, white spots disappear after around eight weeks, which is the amount of time necessary for nails to regrow completely.[9] White spots showing up on all or nearly all nails for longer periods of time (months and years) can be due to one of several reasons. One common explanation is zinc deficiency.[10] [edit] Diagnosis and treatmentA doctor will take a thorough medical history, and may test liver and kidney function. If a zinc deficiency is identified, a diet rich in zinc or zinc supplements may be administered. [edit] References
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