In the heart, a ventricle is a heart chamber which collects blood from an atrium (another heart chamber that is smaller than a ventricle) and pumps it out of the heart. Interventricular means between two or more ventricles (for example the interventricular septum), while intraventricular means within one ventricle (for example an intraventricular block).

In a four-chambered heart, such as that in humans, there are two ventricles: the right ventricle pumps blood into the pulmonary circulation for the lungs, and the left ventricle pumps blood into the systemic circulation through the aorta for the rest of the body. (See Double circulatory system for details.)

Ventricles have thicker walls than the atrium, and thus can withstand lower blood pressure. Comparing the left and right ventricles, the left ventricle has thicker walls because it needs to pump blood to the whole body.

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