USS Missouri may refer to:

• USS Missouri (1841), was a sidewheel frigate launched in 1841 and destroyed by fire in August 1843.

• Missouri, was a side‑wheel steamer, formerly the Confederate ironclad ram Missouri, turned over to the US Navy at the end of the American Civil War, but then scrapped because of her poor construction

• USS Missouri (BB-11), was a Maine-class battleship in service from 1900 to 1922.

• USS Missouri (BB-63), is a decommissioned Iowa-class battleship and the site of the official Japanese surrender of World War II. She is now a floating War Memorial at Pearl Harbor Naval Base, Hawaii.

• USS Missouri (SSN-780), will be a Virginia-class submarine and is currently under construction.

This article includes a list of ships with the same or similar names. If an internal link for a specific ship led you here, you may wish to change the link to point directly to the intended ship article, if one exists.