Type-II collagen Information & Type-II collagen Links at HealthHaven.com

collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital)
Identifiers
Symbol	COL2A1
Alt. symbols	SEDC
Entrez	1280
HUGO	2200
OMIM	120140
RefSeq	NM_001844
UniProt	P02458
Other data
Locus	Chr. 12 q13.11-q13.2

Type-II collagen is the basis for articular cartilage and hyaline cartilage.

It makes up 50% of all protein in cartilage and 85-90% of collagen of articular cartilage.

[edit] See also

Collagen

Type II collagen does form fibers. This fibrillar network of collagen allows cartilage to entrap the proteoglycan aggregate as well as provide tensile strength to the tissue.

[edit] External links

MeSH Collagen+type+II

This article on a gene on chromosome 12 is a stub. You can help Wikipedia by expanding it.

Protein: scleroproteins

Extracellular matrix

Collagen

1-12	type I (COL1A1, COL1A2) · type II (COL2A1) · type III · type IV (COL4A1, COL4A2, COL4A3, COL4A4, COL4A5, COL4A6) · type V (COL5A1, COL5A2, COL5A3) · type VI (COL6A1, COL6A2, COL6A3) · type VII (COL7A1) · type VIII (COL8A1, COL8A2) · type IX (COL9A1, COL9A2, COL9A3) · type X (COL10A1) · type XI (COL11A1, COL11A2) · type XII (COL12A1)

13-29	COL13A1 · COL14A1 · COL15A1 · COL16A1 · COL17A1 · type XVIII (COL18A1, Endostatin) · COL19A1 · COL20A1 · COL21A1 · COL22A1 · COL23A1 · COL24A1 · COL25A1 · COL26A1 · COL27A1 · COL28A1 · COL29A1

Enzymes	Prolyl hydroxylase/Lysyl hydroxylase · Cartilage associated protein/Leprecan · ADAMTS2 · Procollagen peptidase · Lysyl oxidase

Tenascin

Tenascin C · Tenascin X

Laminin

alpha (LAMA1, LAMA2, LAMA3, LAMA4, LAMA5) · beta (LAMB1, LAMB2, LAMB3, LAMB4) · gamma (LAMC1, LAMC2, LAMC3)

Other

ALCAM · Elastin (Tropoelastin) · Vitronectin

Keratin/Cytokeratin

Epithelial keratins (soft alpha-keratins)	type I/chromosome 17 (10, 12, 13, 14, 15, 16, 17, 19, 20) · chromosome 12 (18) · none (21) type II/chromosome 12 (1, 2A, 3, 4, 5, 6A, 6B, 7, 8, 9)

Hair keratins (hard alpha-keratins)	type I/chromosome 17 (31, 32, 33A, 33B, 34, 35, 36, 37, 38) type II/chromosome 12 (81, 82, 83, 84, 85, 86)

Ungrouped alpha	chromosome 17 (23, 24, 25, 26, 27, 28, 39, 40) chromosome 12 (71, 72, 73, 74, 75, 76, 77, 78, 79, 80)

Not alpha	Beta-keratin

Other

Gelatin · Reticulin

see also diseases

Retrieved from "http://en.wikipedia.org/wiki/Type-II_collagen"

Categories: Genes on chromosome 12 | Chromosome 12 gene stubs | Structural proteins

Hidden categories: Protein pages needing a picture