Twentieth century may refer to:

• The 20th century, the period between the years 1901 and 2000 of the Gregorian calendar
• The 20th century BC
• 20th Century Fox
• 20th Century Limited, a passenger train between Chicago and New York City that operated from 1902 to 1967
• Twentieth Century (play), a 1932 play
• Twentieth Century (film), a 1934 film
• Twentieth Century (typeface), a geometric sans-serif typeface.
• 20th Century (cocktail), a cocktail
• Twentieth Century (TV series), a long-running TV documentary series telecast on CBS from 1957 to 1970, and hosted by Walter Cronkite

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