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A parasitic cancer or transmissible cancer is a cancer cell or cluster of cancer cells that can be transmitted from animal to animal. Cancer is not normally a contagious disease, but there are two known exceptions: one in dogs and the other in Tasmanian devils. These cancers have a relatively stable genome as they are transmitted.[1] Because of their transmission, it was initially thought that both diseases were caused by the transfer of viruses, in the manner of cervical cancer caused by HPV.

  • Canine transmissible venereal tumor (CTVT) is sexually transmitted cancer in dogs. It was experimentally transplanted between dogs in 1876 by M. A. Novinsky (1841-1914). A single malignant clone of CTVT cells has colonized dogs worldwide, representing the oldest known malignant cell line in continuous propagation.[3]

[edit] Instances of transmission of human cancer

A malignant fibrous histiocytoma was contracted from a patient by a surgeon when he injured his hand during an operation.[4]

[edit] References

  1. ^ Retrovirology A sexually transmitted parasitic cancer
  2. ^ Pearse, A.-M., Swift, K. (2006). "Allograft theory: Transmission of devil facial-tumour disease" (abstract). Nature 439 (7076): 549. doi:10.1038/439549a. PMID 16452970. http://www.nature.com/nature/journal/v439/n7076/abs/439549a.html. 
  3. ^ Murgia C, Pritchard JK, Kim SY, Fassati A, Weiss RA (August 2006). "Clonal origin and evolution of a transmissible cancer". Cell 126 (3): 477–87. doi:10.1016/j.cell.2006.05.051. PMID 16901782. http://linkinghub.elsevier.com/retrieve/pii/S0092-8674(06)00912-3. 
  4. ^ Gärtner, Hermine-Valeria; Seidl, Christian; Luckenbach, Christine; Schumm, Georg; Seifried, Erhard; Ritter, Horst; Bültmann, Burkhard (1996), "Genetic analysis of a sarcoma accidentally transplanted from a patient to a surgeon.", New England Journal of Medicine 335 (20): 1494–1497, PMID 8890100, http://content.nejm.org/cgi/content/extract/335/20/1494, retrieved 2009-03-29 



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