Tholene was a mentholated lip balm made by the Rosebud Perfume Company of Woodsboro, Maryland. It is notable for its distinctive packaging (empty tins are considered collectible). Today it's sold as "Smith's Mentholated Salve." It was created by druggist, G.F. Smith, who perfected Rosebud Salve. The mentholated salve is a cooling salve designed to soothe minor skin irritations, especially those associated with colds, allergies, minor burns, and insects stings.