Template:Antithrombotics Information & Template:Antithrombotics Links at HealthHaven.com

Template:Antithrombotics Information & Template:Antithrombotics Links at HealthHaven.com

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Antithrombotics (thrombolytics, anticoagulants and antiplatelet drugs) (B01)

Antiplatelet drugs

Glycoprotein IIb/IIIa inhibitors	Abciximab • Eptifibatide • Tirofiban

ADP receptor/P2Y₁₂ inhibitors	(Thienopyridines) Clopidogrel • Ticlopidine • Prasugrel

Prostaglandin analogue (PGI2)	Beraprost • Prostacyclin • Iloprost • Treprostinil

COX inhibitors	Acetylsalicylic acid/Aspirin # • Aloxiprin • Carbasalate calcium

Other	Ditazole • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal

Vitamin K antagonists
(inhibit II, VII, IX, X)

coumarins: Acenocoumarol • Coumatetralyl • Dicoumarol (Dicumarol) • Ethyl biscoumacetate • Phenprocoumon • Warfarin

1,3-Indandiones: Clorindione • Diphenadione • Phenindione

other: Tioclomarol

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	low molecular weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) oligosaccharides (Fondaparinux, Idraparinux) heparinoid (Danaparoid, Sulodexide, Dermatan sulfate)

Direct Xa inhibitors	xabans (Apixaban, Otamixaban, Rivaroxaban)

Direct thrombin (II) inhibitors

bivalent: Hirudin (Bivalirudin, Lepirudin, Desirudin)

univalent: Argatroban • Dabigatran • Melagatran‡ • Ximelagatran‡

Other

Defibrotide • Ramatroban • Antithrombin III • Protein C (Drotrecogin alfa)

Thrombolytic drugs/
fibrinolytics

plasminogen activators: TPA (Alteplase, Reteplase, Tenecteplase) • UPA (Urokinase, Saruplase) • Streptokinase # • Anistreplase • Monteplase

other serine endopeptidases: Ancrod • Fibrinolysin

Citrate • EDTA • Oxalate

^#WHO-EM. ^‡Withdrawn from market. CLINICAL TRIALS: ^†Phase III. ^§Never to phase III

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