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Sulfacetamide - multiple sclerosis encyclopaedia mult-sclerosis.org | Rosacea Topical Treatments: Sodium Sulfacetamide rosaceaguide.com | PLEXION® (sodium sulfacetamide 10% and sulfur 5%) plexion.com |
Sulfacetamide is a sulfonamide antibiotic.
[edit] UsesSulfacetamide 10% topical lotion, sold under the brand name Klaron or Ovace, is approved for the treatment of acne and seborrheic dermatitis.[1] When combined with sulfur, it is sold under the brand name PLEXION and AVAR which is a 10% Sodium Sulfacetamide 5% Sulfur product. Sulfacetamide has been investigated for use in the treatment of pityriasis versicolor[2] and rosacea.[3] It may also have anti-inflammatory properties when used to treat blepharitis or even Conjunctivitis.[citation needed] It has been suggested that sulfacetamide may also serve as a treatment for mild forms of hidradenitis suppurativa.[citation needed] Sodium Sulfacetamide has antibacterial activity and is used to control acne. Products containing sodium sulfacetamide (an antibacterial) and sulfur (a keratolytic) are commonly promoted for the treatment of acne rosacea (rosacea with papules, pustules, or both). [edit] Adverse EffectsThe most common adverse side effects of sodium sulfacetamide/sulfur combination products are local irritation and contact dermatitis. Sodium Sulfacetamide should not be used by individuals who have a sensitivity to sulfur of sulfa. [edit] ApplicationsThere are several prescription topical applications of Sodium Sulfacetamide. The line of OVACE products include a foam, shampoo, cream and wash. Ovace is sulfur free and fragrance free so there is no unpleasant odor after application and it is non-irritating. It also does not contain sodium metabisulfite which is associated with allergic-type reactions in certain susceptible individuals. Some research indicates that sulfacetamide derivatives may act as antifungals by an CYP51A1-independent mechanism.[4] [edit] GlossarySeborrheic Dermatitis A common, chronic, inflammatory, erythematous (red) scaling eruption that occurs in areas where there are a large number of sebaceous glands, scalp, sides of nose, hairline, eyebrows, eyelids, behind the ears and mid chest. Other areas include the navel, groin, armpits, breasts and buttocks.
Papules Solid elevations of the skin; bumps. [edit] References
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