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The stratum spinosum (or spinous layer) is a layer of the epidermis found between the stratum granulosum and stratum basale.[1] This layer is also referred to as the "spinous" or "prickle-cell" layer.[2] This apearence is due to desmosomal connections of adjacent cells. The cells in the stratum spinosum produce and secrete bipolar lipids which prevent evaporation, helping to "water-proof" the skin. Keratinization begins in the stratum spinosum.[3]

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[edit] References

  1. ^ James, William; Berger, Timothy; Elston, Dirk (2005) Andrews' Diseases of the Skin: Clinical Dermatology (10th ed.). Saunders. Page 2. ISBN 0721629210.
  2. ^ McGrath, J.A.; Eady, R.A.; Pope, F.M. (2004). Rook's Textbook of Dermatology (Seventh Edition). Blackwell Publishing. Pages 3.7-3.8. ISBN 9780632064298.
  3. ^ Marks, James G; Miller, Jeffery (2006). Lookingbill and Marks' Principles of Dermatology (4th ed.). Elsevier Inc. Page 6. ISBN 1-4160-3185-5.



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