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A spine is a hard, thorny or needle-like structure which occurs on various animals. Animals such as porcupines and sea urchins grow spines as a self-defense mechanism. Spines are often formed of keratin. Other animals with spines are hedgehogs and spiny mice.


In the context of neuroscience, is also used as shorthand for dendritic spines, tiny protusions on the surface of nerve cells that are contacted by presynaptic terminals.




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