Sodoku
Classification and external resources
ICD-10	A25.0
ICD-9	026.0
DiseasesDB	32803
MedlinePlus	001348
MeSH	D011906

Sodoku is a bacterial zoonotic disease. It is caused by outnumbered spirochaete Spirillum minus. It is a form of rat-bite fever (RBF).

[edit] Causes

The infections are acquired through rat bites or scratches. It can occur as nosocomial infections (ie, acquired from hospitals), or due to exposure or close associations with animals preying on rats, mice, squirrels etc. Sodoku is mostly seen in Asia. The incubation period is 4 to 28 days.

[edit] Presentation and symptoms

The initial scratch or wound caused by a bite from a carrier rodent will result in mild inflammatory reactions and ulcerations. The wounds may heal initially, but reappear with the onset of symptoms. The symptoms include recurring fever, with body temperature 101-104 °F (38-40°C). The fever lasts for 2-4 days but recur generally at 4-8 weeks. This cycle may continue for months or years together. The other symptoms include regional lymphadenitis, malaise and headache. The complications include myocarditis, endocarditis, hepatitis, splenomegaly and meningitis.

[edit] Prognosis

Mortality ranges from 6-10%.

v • d • e Infectious diseases · Bacterial diseases: non-proteobacterial G- (primarily A00-A79, 001-041,080-109) Spirochaete Spirochaetaceae Treponema Treponema pallidum (Syphilis/Bejel, Yaws) · Treponema carateum (Pinta) · Treponema denticola Borrelia Borrelia recurrentis (Relapsing fever) · Borrelia burgdorferi (Lyme disease, Erythema chronicum migrans, Neuroborreliosis) Leptospiraceae Leptospira Leptospira interrogans (Leptospirosis) Spirillaceae Spirillum Spirillum minus (Rat-bite fever/Sodoku) Chlamydiae Chlamydophila Chlamydophila psittaci (Psittacosis) · Chlamydophila pneumoniae Chlamydia Chlamydia trachomatis (Chlamydia, Lymphogranuloma venereum, Trachoma) Bacteroidetes Bacteroides fragilis · Capnocytophaga canimorsus · Porphyromonas gingivalis · Prevotella intermedia · Bacteroides forsythus Fusobacteria Fusobacterium necrophorum (Lemierre's syndrome) · Fusobacterium nucleatum · Fusobacterium polymorphum