San Salvador may refer to:
- San Salvador, capital of the Republic of El Salvador
- San Salvador Department, department of El Salvador
- San Salvador Island, in the Bahamas
- Isla San Salvador, Ecuador
- San Salvador Atenco, in the state of Mexico
- San Salvador, Entre Ríos, a city in Argentina
- San Salvador, Peru, a city in Peru
- San Salvador District, Paraguay
- San Salvador de Jujuy, a city in Argentina
- San Salvador (volcano), in El Salvador
- San Salvador F.C., a football (soccer) club of San Salvador.
- San Salvador (band), an Australian reggae rock band
- San Salvador (Irish band), an Irish rock band
- San Salvador (Guipúzcoan squadron), a ship of the Spanish Armada (in the Guipúzcoan squadron; there was another in the Spanish Armada in a different squadron)
- San Salvador, Venice - the Chiesa di San Salvatore (of the Holy Saviour) is a church in Venice, northern Italy.
San Salvador may also be:
- The first island Christopher Columbus reached when he discovered the Americas. See Guanahani
- Salvator of Horta (San Salvador), Roman Catholic saint