Saint-Gaudens, Saint Gaudens, and St. Gaudens may refer to:

• Arrondissement of Saint-Gaudens, an arrondissement (district) of France
• Augustus Saint-Gaudens (1848-1907), an Irish-born American sculptor
• Louis St. Gaudens (1854-1913), an American sculptor and brother of Augustus Saint-Gaudens
• Saint-Gaudens, Haute-Garonne, a commune in the Haute-Garonne department in southwestern France
• Saint-Gaudens Bears, a French rugby league team
• St. Gaudens Double Eagle, a twenty dollar gold coin designed by Augustus Saint-Gaudens
• Saint-Gaudens National Historic Site, the home, gardens, and studios of Augustus Saint-Gaudens in Cornish, New Hampshire

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