SPA can refer to: [edit] As an abbreviation - Saddle point approximation, a term used in quantum field theory
- Sales and Purchase Agreement, a legal term for selling a company
- Sales Per Admission, a term used in film exhibition; product/food sales per ticket sold
- Saudi Press Agency
- Science Practical Assessment, the Singapore's assessment of students in science practicals
- Scintillation Proximity Assay, an assay used for biochemical development and screening
- School of Planning and Architecture, the India's premier architecture and city-planning institution, located in Delhi
- Scottish Publishers Association, a trade association
- Secure Password Authentication
- Self-Propelled Artillery
- Sense Plan Act, an artificial intelligence methodology used in robotics
- Separation Party of Alberta
- Seven Party Mujahideen Alliance, the alliance of Afghan mujahideen guerrillas against the Soviets
- Seychelles Port Authority
- Simple power analysis, a type of cryptographic attack
- Single Packet Authorization
- Single Page Application, a web application that is entirely contained on the client-side typically using a combination of HTML, JavaScript, and Cascading Style Sheets
- Single Pitch Award, a qualification for the supervision of rock climbing awarded by the National Governing Bodies for Mountaineering in the UK
- Share purchase agreement, a contract to sell/buy shares
- Special pale ale, a term used to designate a certain type of pale ale
- Socialist Party of America
- Socialist Party of Australia
- Società per Azioni, an Italian corporate form used by major public corporations quoted on the Italian stock exchange
- Società Piemontese Automobili, a Torino-based car manufacturer (1908-1926)
- Société protectrice des animaux, an animal welfare organization in France
- Software Publishers Association, now known as the Software and Information Industry Association (SIIA)
- Sp.a, the "Socialistische Partij - Anders" (Socialist Party - Differently), the socialist party in Flanders
- Spathoglottis, an orchid genus
- Special Price Agreement, price agreement with vendor for specific project
- Special Prorate Agreement, an agreement between airlines, serves as addendum for Interline agreement
- Special Protection Area, a European Union nature conservation designation
- spontaneous platelet aggregation, a medical term used in connection with coagulation tests
- Stimulation-produced analgesia, a term related to the GATE theory in physiology of pain
- St. Paul Academy and Summit School, a private K-12 school in Saint Paul, Minnesota
- St Patrick's Athletic, a football (Soccer) club in Ireland
- Stochastic process algebra
- Student Peace Alliance, a student led peace organization in the United States of America
- subpoena
- Substance P antagonist, a term used in biochemistry
- Summer Performing Arts Company, a summer educational theatre program in Grand Forks, North Dakota, United States
- Supreme People's Assembly, the parliament of the Democratic People's Republic of Korea
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