Roth's spots are retinal hemorrhages with white or pale centers composed of coagulated fibrin. They are typically observed via fundoscopy (using an ophthalmoscope to view inside the eye) or slit lamp exam.

They are usually caused by immune complex mediated vasculitis often resulting from bacterial endocarditis. Roth's spots may be observed in leukemia, diabetes, subacute bacterial endocarditis, pernicious anaemia, ischemic events, and rarely in HIV retinopathy.

Roth's spots are named after Moritz Roth.^[1][2]

[edit] See also

• Osler's nodes
• Janeway lesion

[edit] References

[edit] External links

• Image at Nature.com

v • d • e Eponymous medical signs for eyes and ears Eyes Adnexa lacrimal: Schirmer's test eyelid: Abadie's sign · Boston's sign · Dalrymple's sign · Stellwag's sign Globe pupil: Argyll Robertson pupils · Adie pupil · Marcus Gunn pupil iris: Fleischer ring · Kayser-Fleischer ring · Brushfield spots · Lisch nodule conjunctiva: Bitot's spots retina: Hollenhorst plaque · Roth's spot other: Alexander's law · Hirschberg test · Siegrist streaks · Hudson-Stahli line Ears auditory: Rinne test · Weber test vestibular: Unterberger test eye navs: anat/adnexa anat/pathways/physio/dev, noncongen/congen/neoplasia, eponymous signs, proc ear navs: anat/pathways/physio/dev, noncongen/congen, eponymous signs, proc

v • d • e Eponymous medical signs for circulatory system Heart disease Heart murmur Systolic heart murmur: benign paediatric heart murmur (Still's murmur) Diastolic heart murmur: pulmonic regurgitation (Graham Steell murmur) · aortic insufficiency (Austin Flint murmur) Aortic insufficiency Watson's water hammer pulse/Corrigan pulse · De Musset's sign · Duroziez's sign · Müller's sign · Quincke's sign · Austin Flint murmur · Mayne's sign Other endocardium endocarditis: Roth's spot · Janeway lesion/Osler's node · Bracht-Wachter bodies Pericardium cardiac tamponade/pericardial effusion: Beck's triad · Ewart's sign Other rheumatic fever: Anitschkow cell · Aschoff body EKG (Osborn wave) angina pectoris (Levine's sign) Vascular disease Arterial aortic aneurysm (Cardarelli's sign, Oliver's sign) · pulmonary embolism (McConnell's sign) · radial artery sufficiency (Allen's test) · pseudohypertension (Osler's sign) · thrombus (Lines of Zahn) Adson's sign · arteriovenous fistula (Nicoladoni sign) Venous Friedreich's sign · Caput medusae · Kussmaul's sign · DVT (Pratt's sign, Lisker's sign) · Trendelenburg's test · superior vena cava syndrome (Pemberton's sign) heart navs: anat/physio/dev, noncongen/congen/neoplasia, symptoms+signs/eponymous, proc vascular navs: anat/physio/dev, noncongen/systemic vasculitis/congen/neoplasia, symptoms+signs/eponymous, proc

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