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A reproductive system disease is any disease that impairs the ability to reproduce. Such diseases may arise from genetic or congenital abnormalities, such as hermaphroditism, from functional problems such as impotence or infertility or reproductive tract infections, such as sexually transmitted diseases.

Reproductive tract infection (RTI) are infections that affect the reproductive tract, which is part of the Reproductive System. For females, reproductive tract infections can be in either the upper reproductive tract (fallopian tubes, ovary and uterus), and the lower reproductive tract (vagina, cervix and vulva); for males these infections are at the penis, testicles, urethra or the sperm tube. The three types of reproductive tract infections are endogenous infections, iatrogenic infections and the more commonly known sexually transmitted infections. Each has its own specific causes and symptoms, caused by a bacterium, virus, fungus or other organism. Some infections are easily treatable and can be cured, some are more difficult, and some are non curable

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