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Remikiren
Systematic (IUPAC) name
(2S)-2-[(2R)-2-benzyl-3-(2-methylpropane-2-sulfonyl)propanamido]-N-[(2R,3S,4R)-1-cyclohexyl-4-cyclopropyl-3,4-dihydroxybutan-2-yl]-3-(1H-imidazol-4-yl)propanamide
Identifiers
CAS number 126222-34-2
ATC code C09XA01
PubChem 5462340
DrugBank APRD00163
Chemical data
Formula C33H50N4O6S 
Mol. mass 630.839 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 83%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?


Remikiren is a renin inhibitor under development for the treatment of hypertension (high blood pressure). It was first developed by Hoffmann–La Roche in 1996.[1]

[edit] References

  1. ^ Richter WF, Whitby BR, Chou RC (1996). "Distribution of remikiren, a potent orally active inhibitor of human renin, in laboratory animals". Xenobiotica 26 (3): 243–54. PMID 8730917. 



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