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Ramón de los Santos
Pitcher
Born: January 19, 1949 (1949-01-19) (age 60)
Santo Domingo, Dominican Republic
Batted: Left Threw: Left 
MLB debut
August 211974 for the Houston Astros
Last MLB appearance
October 21974 for the Houston Astros
Career statistics
Win-Loss record     1-1
ERA     2.19
Strikeouts     7
Teams

Ramón (Genero) de los Santos (born January 19, 1949 in Santo Domingo, Dominican Republic) is a former Major League Baseball relief pitcher. The left-hander signed as a free agent with the Houston Astros on April 9, 1972 and played for them in 1974.

De los Santos was called up to Houston in August 1974 after a season dominating hitters in the Double-A Southern League. Pitching in 42 games for the Columbus Astros, he struck out 73 batters in 76 innings and allowed only 11 earned runs. He was 7-4 with an ERA of 1.30.

On August 21, 1974 de los Santos made his major league debut in relief against the New York Mets at the Astrodome. He retired the first batter he faced, right fielder Rusty Staub, then struck out first baseman John Milner to end the 6th inning. In 2.2 innings that night he gave up two hits, three walks, and two unearned runs, and the Astros lost, 10-2. They had made five errors during the game.

De los Santos won his first and only big league game one week later at Shea Stadium. He retired Mets shortstop Bud Harrelson, the last hitter in the bottom of the 9th, and then teammate Cliff Johnson hit a home run in the top of the 10th to win the game, 3-2.

Season and career totals for 12 games include a 1-1 record and 5 games finished. In 12.1 innings pitched he gave up 3 earned runs for an ERA of 2.19.

In 1975 de los Santos pitched in both Triple-A and Double-A, and was drafted by the St. Louis Cardinals organization after the season (December 9), but never again appeared in a major league game.

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