Pyridoxamine
IUPAC name	4-(aminomethyl)-5-(hydroxymethyl)-2-methylpyridin-3-ol
Identifiers
CAS number	85-87-0 Y
PubChem	1052
SMILES	Oc1c(CN)c(cnc1C)CO
ChemSpider ID	1023
Properties
Molecular formula	C8H12N2O2
Molar mass	168.19 g mol−1
Y (what is this?)  (verify) Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Pyridoxamine is one of the compounds composing vitamin B6, along with pyridoxal and pyridoxine. Pyridoxamine is converted to the biologically active form, pyridoxal 5-phosphate, and inhibits formation of advanced glycation endproducts.

Pyridoxamine is based on a pyridine ring, with hydroxyl, methyl, aminomethyl, and hydroxymethyl substituents. It differs from pyridoxine by the subsitituent at the 4-position.

Pyridoxamine is used as a dietary supplement, often as the hydrochloride salt, pyridoxamine dihydrochloride. However, in the United States, the FDA ruled in January 2009 that pyridoxamine must be regulated as a pharmaceutical drug because it is the active ingredient in Pyridorin, a drug designed to prevent the progression of diabetic nephropathy.^[1] As a consequence, pyridoxamine can no longer be marketed in the United States as a dietary supplement.

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