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A proinflammatory cytokine is a cytokine which promotes systemic inflammation.

Examples include IL-1[1] and TNF alpha.[2]

[edit] References

  1. ^ Dinarello CA (August 2000). "Proinflammatory cytokines". Chest 118 (2): 503–8. PMID 10936147. http://www.chestjournal.org/cgi/pmidlookup?view=long&pmid=10936147. 
  2. ^ Cheung CY, Poon LL, Lau AS, et al. (December 2002). "Induction of proinflammatory cytokines in human macrophages by influenza A (H5N1) viruses: a mechanism for the unusual severity of human disease?". Lancet 360 (9348): 1831–7. PMID 12480361. http://linkinghub.elsevier.com/retrieve/pii/S0140673602117727. 
v • d • e
Cell signaling: cytokines
By family
IL-1 superfamily
1 (1Ra) · 18 · 33
IL-6 like/gp130 using
IL-10 family
10 · 19 · 20 · 22 · 24 · 26
28 · 29
2/15 · 3 · 4 · 7 · 9 · 13 · 21
IL-12 family
12 · 23 · 27 · 35
Other
5 · 8 · 14 · 16 · 17/25 (A) · 32  · 34
CCL
1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17 · 18 · 19 · 20 · 21 · 22 · 23 · 24 · 25 · 26 · 27 · 28
CXCL
1 · 2 · 3 · 4 · 5 · 6 · 7 · 8 · 9 · 10 · 11 · 12 · 13 · 14 · 15 · 16 · 17
CX3CL
XCL
1 · 2
Main
TNF (ligand) superfamily
CD70 · CD153 · CD154
alpha (Pegylated 2a, Pegylated 2b), beta (1a, 1b)
28 · 29
Other
By function
Retrieved from "http://en.wikipedia.org/wiki/Proinflammatory_cytokine"



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