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Pia mater
Gray770.png
Diagrammatic transverse section of the medulla spinalis and its membranes. (At border, dura mater is black line, arachnoid mater is blue line, and pia mater is red line.)
Gray767.png
The medulla spinalis and its membranes.
Gray's subject #193 878
MeSH Pia+Mater

The pia mater (pronounced /ˈpaɪ.ə ˈmeɪtər/, from Latin "tender mother") is the delicate innermost layer of the meninges—the membranes surrounding the brain and spinal cord.

The thin, mesh-like pia mater closely envelops the entire surface of the brain, running down into the fissures of the cortex. It joins with the ependyma which lines the ventricles to form choroid plexuses that produce cerebrospinal fluid.

In the spinal cord, the pia mater attaches to the dura mater by the denticular ligaments through the arachnoid membrane.

The pia mater is a neural crest derivative.

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