Phenindione Information & Phenindione Links at HealthHaven.com

Phenindione
Systematic (IUPAC) name

2-phenyl-1H-indene-1,3(2H)-dione
Identifiers
CAS number	83-12-5
ATC code	B01AA02
PubChem	4760
DrugBank	APRD00166
Chemical data
Formula	C₁₅H₁₀O₂
Mol. mass	222.239 g/mol
Pharmacokinetic data
Bioavailability	?
Protein binding	88%
Metabolism	?
Half life	5 to 10 hours
Excretion	?
Therapeutic considerations
Pregnancy cat.	D(AU) Passes into breast milk
Legal status
Routes	Oral

Phenindione is an anticoagulant which functions as a Vitamin K antagonist.

Hypersensitivity has been observed.^[1]

[edit] References

Glycoprotein IIb/IIIa inhibitors	Abciximab • Eptifibatide • Tirofiban

ADP receptor/P2Y₁₂ inhibitors	(Thienopyridines) Clopidogrel • Ticlopidine • Prasugrel

Prostaglandin analogue (PGI2)	Beraprost • Prostacyclin • Iloprost • Treprostinil

COX inhibitors	Acetylsalicylic acid/Aspirin # • Aloxiprin • Carbasalate calcium

Other	Ditazole • Cloricromen • Dipyridamole • Indobufen • Picotamide • Triflusal

Factor Xa inhibitors
(with some II inhibition)

Heparin group/ glycosaminoglycans/ (bind antithrombin)	low molecular weight heparin (Bemiparin, Certoparin, Dalteparin, Enoxaparin, Nadroparin, Parnaparin, Reviparin, Tinzaparin) oligosaccharides (Fondaparinux, Idraparinux) heparinoid (Danaparoid, Sulodexide, Dermatan sulfate)

Direct Xa inhibitors	xabans (Apixaban, Otamixaban, Rivaroxaban)