Pan-American or Pan American may refer to:

• Pan-Americanism, an integrationist movement among the nations of the Americas
• Pan American Union, later the Organization of American States
• Pan American Health Organization
• Pan-American Highway
• Pan-American Games
• Pan American World Airways, a defunct U.S airline
• Pan-American Exposition, New York, United States, 1901
• Pan-American (train), a L&N train that ran from Cincinnati to New Orleans
• Pan American Center, in New Mexico, United States
• Pan American Christian Academy, in São Paulo, Brazil
• Pan American Silver Corporation, a Canadian mining company
• Pan American (band), an ambient/post-rock music ensemble

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