An analgesic, also known as a painkiller, is a group of drugs.

Painkiller(s) or pain killer may also refer to:

An album:

• Painkiller (Judas Priest album), by Judas Priest
• Painkiller (Krokus album), by Krokus
• Painkillers (album), a 1993 album by Babes in Toyland
• Pain Killer (Energy Orchard album), by Energy Orchard
• Pain Killer, by Futon

A song:

• "Painkiller" (Judas Priest song), from the album Painkiller
• "Painkiller" (Freestylers song), featuring Pendulum and SirReal
• "Painkiller", a 2003 single by Turin Brakes
• "Painkiller", the B-side of "Barrel of a Gun", a single by Depeche Mode
• "Painkillers", by Cannibal Ox from their 2001 album The Cold Vein
• "Painkillers", by Everlast from his 1998 album Whitey Ford Sings the Blues

Other:

• Painkiller (band), fronted by John Zorn and Bill Laswell
• Painkiller (video game), a first person shooter for the PC and Xbox
• Painkiller (cocktail), a rum cocktail

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