PRC is an abbreviation for People's Republic of China. PRC or .prc may also refer to: - Prince Royal's College, a private school in Chiang Mai, Thailand
- Permanent Resident Card, an type of identification card
- Communist Refoundation Party, an Italian reformed communist party
- Ernest A. Love Field (IATA code: PRC), a public airport near Prescott, Arizona
- Palestine Red Crescent Society, a humanitarian organization
- Peterborough Regional College
- Phase response curve showing biological responses to light and to exogenous melatonin in animals
- Popular Resistance Committees, various Palestinian militant organizations which operate in the Gaza Strip
- Postal Regulatory Commission, an independent regulatory agency
- Practical reserve capacity, a value of the spare capacity for traffic at a traffic signal junction
- Presbyterian Reformed Church
- Prestige class (PrC), in the Dungeons & Dragons role-playing game
- Producers Releasing Corporation, one of the larger Hollywood production conglomerates of Poverty Row of the late 30s-mid 40s
- Professional Regulation Commission, an agency of the government of the Republic of the Philippines
- Project Runway Canada, Canadian version of Project Runway, a television show
- Protestant Reformed Churches in America, a Protestant denomination of 27 churches and over 7,000 members
- Regionalist Party of Cantabria, the second oldest political party in the Spanish Autonomous Community of Cantabria
- Photosynthetic reaction center, the molecular unit responsible for absorbing light in photosynthesis
- PlayMakers Repertory Company, the theater company of the University of North Carolina at Chapel Hill, Department of Dramatic Arts
- Portable Radio, Communication, an example is the AN/PRC-77 Portable Transceiver
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