Oxotremorine Information & Oxotremorine Links at HealthHaven.com

	Oxotremorine
	Systematic (IUPAC) name
	1-(4-pyrrolidin- 1-ylbut- 2-yn- 1-yl) pyrrolidin- 2-one
	Identifiers
CAS number	70-22-4
ATC code	none
PubChem	?
	Chemical data
Formula	C12H18N2O
Mol. mass	206.28
	Pharmacokinetic data
Bioavailability	?
Metabolism	?
Half life	?
Excretion	?
	Therapeutic considerations
Pregnancy cat.	?
Legal status
Routes	?
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Oxotremorine is a synthetic alkaloid and is a muscarinic agonist^[1] in that it will bind to muscarinic acetylcholine receptors. It is therefore a parasympathomimetic.

Specifically, oxotremorine is a non-selective muscarinic receptor agonist.

In addition, it also produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs.^[2]

[edit] References

^ Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013.
^ Craig, C. R., Stitzel, R. E., Modern Pharmacology. Little, Brown. Boston, 2006.

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[pmid8330013-0] Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013.

[1] Craig, C. R., Stitzel, R. E., Modern Pharmacology. Little, Brown. Boston, 2006.

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