Oxotremorine:
Oxotremorine is a synthetic alkaloid and is a muscarinic agonist[1] in that it will bind to muscarinic acetylcholine receptors. It is therefore a parasympathomimetic.
Specifically, oxotremorine is a non-selective muscarinic receptor agonist.
In addition, it also produces ataxia, tremor and spasticity, similar to those symptoms seen in Parkinsonism, and has thus become a research tool in experimental studies aimed at determining more effective anti-Parkinsonian drugs. [2]
[edit] References
- ^ Tang C, Castoldi AF, Costa LG (April 1993). "Effects of the muscarinic agonist oxotremorine on membrane fluidity in rat lymphocytes". Biochem. Mol. Biol. Int. 29 (6): 1047–54. PMID 8330013.
- ^ Craig, C. R., Stitzel, R. E., Modern Pharmacology. Little, Brown. Boston, 2006.
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