"Ovaria" redirects here. This is also a proposed section and a synonym of Solanum.

Ovary
Internal reproductive organs of human female
Latin	ovarium
Gray's	subject #266 1254
Artery	ovarian artery, uterine artery
Vein	ovarian vein
Nerve	ovarian plexus
Lymph	lumbar lymph nodes
MeSH	Ovary
Dorlands/Elsevier	Ovary

The ovary is an ovum-producing reproductive organ, often found in pairs as part of the vertebrate female reproductive system. Ovaries in females are homologous to testes in males, in that they are both gonads and endocrine glands.

[edit] Human anatomy

Ovaries are oval shaped and, in the human, measure approximately 3 cm x 1.5 cm x 1.5 cm (about the size of a Greek olive). The ovary (for a given side) is located in the lateral wall of the pelvis in a region called the ovarian fossa. The fossa usually lies beneath the external iliac artery and in front of the ureter and the internal iliac artery.

The ovaries aren't attached to the fallopian tubes but to the outer layer of the uterus via the ovarian ligaments. Usually each ovary takes turns releasing eggs every month; however, if there was a case where one ovary was absent or dysfunctional then the other ovary would continue providing eggs to be released.

PLEASE NOTE: This 'ovary' info says: "The ovaries aren't attached to the fallopian tubes" (para above) however the 'fallopian tubes' info says: "The tube connects the ovary to the uterus".

[edit] Hormones

Ovaries secrete both estrogen and progesterone. Estrogen is responsible for the appearance of secondary sex characteristics of females at puberty and for the maturation and maintenance of the reproductive organs in their mature functional state. Progesterone functions with estrogen by promoting cyclic changes in the endometrium (it prepares the endometrium for pregnancy), as well as by helping maintain the endometrium in a healthy state during pregnancy.

[edit] Ligaments

In the human the paired ovaries lie within the pelvic cavity, on either side of the uterus, to which they are attached via a fibrous cord called the ovarian ligament. The ovaries are uncovered in the peritoneal cavity but are tethered to the body wall via the suspensory ligament of the ovary. The part of the broad ligament of the uterus that covers the ovary is known as the mesovarium. Thus, the ovary is the only organ in the human body which is totally invaginated into the peritonium, making it the only interperitoneal organ (not to be confused with intraperitoneal).

[edit] Extremities

There are two extremities to the ovary:

• The end to which the uterine tube attach is called the tubal extremity.
• The other extremity is called the uterine extremity. It points downward, and it is attached to the uterus via the ovarian ligament.

[edit] Histology

[edit] Cell Types

• Follicular Cells - flat epithelial cells that originate from surface epithelium covering the ovary
• granulosa cells - surrounding follicular cells have change from flat to cuboidal and proliferated to produce a stratified epithelium
• Gametes^[1]

Section of the ovary of a newly born child. Germinal epithelium is seen at top. Primitive ova are seen in their cell-nests. The Genital cord or genital ridge is still discernible in this young child. A blood vessel and an ovarian follicle is also seen

• The outermost layer is called the germinal epithelium.
• The tunica albuginea covers the cortex.
• The ovarian cortex consists of ovarian follicles and stroma in between them. Included in the follicles are the cumulus oophorus, membrana granulosa (and the granulosa cells inside it), corona radiata, zona pellucida, and primary oocyte. The zona pellucida, theca of follicle, antrum and liquor folliculi are also contained in the follicle. Also in the cortex is the corpus luteum derived from the follicles.
• The innermost layer is the ovarian medulla. It can be hard to distinguish between the cortex and medulla, but follicles are usually not found in the medulla.

[edit] In other animals

Ovaries of some kind are found in the female reproductive system of many animals that employ sexual reproduction, including invertebrates. However, they develop in a very different way in most invertebrates than they do in vertebrates, and are not truly homologous.^[2]

Many of the features found in human ovaries are common to all vertebrates, including the presence of follicular cells, tunica albuginea, and so on. However, many species produce a far greater number of eggs during their lifetime than do humans, so that, in fish and amphibians, there may be hundreds, or even millions of fertile eggs present in the ovary at any given time. In these species, fresh eggs may be developing from the germinal epithelium throughout life. Corpora lutea are found only in mammals, and in some elasmobranch fish; in other species, the remnants of the follicle are quickly resorbed by the ovary. In birds, reptiles, and monotremes, the egg is relatively large, filling the follicle, and distorting the shape of the ovary at maturity.^[2]

Amphibians and reptiles have no ovarian medulla; the central part of the ovary is a hollow, lymph-filled space. The ovary of teleosts is also often hollow, but in this case, the eggs are shed into the cavity, which opens into the oviduct.^[2]

Although most normal female vertebrates have two ovaries, this is not the case in all species. In birds and platypuses, the right ovary never matures, so that only the left is functional. In some elasmobranchs, the reverse is true, with only the right ovary fully developing. In the primitive jawless fish, and some teleosts, there is only one ovary, formed by the fusion of the paired organs in the embryo.^[2]

[edit] Additional images

Uterus and uterine tubes	Organs of the female reproductive system.	Ovary	An ovary about to release an egg.
Vessels of the uterus and its appendages, rear view.	Broad ligament of adult, showing epoöphoron.	Uterus and right broad ligament, seen from behind.	Female pelvis and its contents, seen from above and in front.
Arteries of the female reproductive tract: uterine artery, ovarian artery and vaginal arteries.

[edit] References

This article includes a list of references, related reading or external links, but its sources remain unclear because it lacks inline citations. Please improve this article by introducing more precise citations where appropriate. (June 2008)

[edit] External links

• [1] From the American Medical Association
• [2] Merck Online Medical Library: Female Reproductive System

[edit] See also

Look up ovary in Wiktionary, the free dictionary.

• Ovarian disease
• Oophorectomy
• Menopause
• Ovum