Obligate could be: - An adjective meaning "by necessity" (antonym facultative) and used mostly in biology, especially in the phrases:
- Obligate parasite, a parasite that cannot survive without its host
- Obligate intracellular parasite, a parasitic microorganism that cannot reproduce outside their host cell
- Obligate aerobe, an organism that cannot survive without oxygen
- Obligate anaerobe, an organism that cannot survive in the presence of oxygen
- Obligate air-breather, a complex organism which obtains required oxygen directly from the atmosphere through respiration rather than extracting dissolved oxygen from water, as, for example, the South American lungfish
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