Nitrofuran Information & Nitrofuran Links at HealthHaven.com

Nitrofurans are a class of drugs typically used as antibiotics or antimicrobials. The defining structural component is a furan ring with a nitro group.

Members of this class of drugs include:

Furazolidone, antibacterial
Furylfuramide
Nitrofurantoin, antibacterial
Nitrofurazone, antibacterial
Nifuratel
Nifurtoinol, antibacterial
Nifuroxazide, antibiotic
Nifurtimox, antiparasitic
Nifurzide, anti-infective

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MeSH Nitrofurans

This pharmacology-related article is a stub. You can help Wikipedia by expanding it.

Antibacterials: nucleic acid inhibitors (J01E, J01M)

Antifolates
(inhibits
purine metabolism,
thereby inhibiting
DNA and RNA synthesis)

DR inhibitor

2,4-Diaminopyrimidine (Trimethoprim^#, Brodimoprim, Tetroxoprim, Iclaprim^†)

Sulfonamides
(DS inhibitor)

Short- acting	Sulfaisodimidine · Sulfamethizole · Sulfadimidine · Sulfapyridine · Sulfafurazole · Sulfanilamide (Prontosil) · Sulfathiazole · Sulfathiourea

Intermediate- acting	Sulfamethoxazole · Sulfadiazine^# · Sulfamoxole

Long- acting	Sulfadimethoxine · Sulfalene · Sulfametomidine · Sulfametoxydiazine · Sulfamethoxypyridazine · Sulfaperin · Sulfamerazine · Sulfaphenazole · Sulfamazone

Other/ungrouped

sulfanilamide (Sulfacetamide, Sulfametrole)

Combinations

Sulfamethoxazole and trimethoprim^#

Topoisomerase
inhibitors/
quinolones/
(inhibits
DNA replication)

1st generation

Cinoxacin^‡ · Flumequine · Nalidixic acid · Oxolinic acid · Pipemidic acid · Piromidic acid · Rosoxacin

Fluoroquinolones

2nd generation	Ciprofloxacin^# · Enoxacin^‡ · Fleroxacin^‡ · Lomefloxacin · Nadifloxacin · Ofloxacin · Norfloxacin · Pefloxacin · Rufloxacin

3rd generation	Balofloxacin · Grepafloxacin^‡ · Levofloxacin · Pazufloxacin · Sparfloxacin^‡ · Temafloxacin^‡ · Tosufloxacin

4th generation	Besifloxacin · Clinafloxacin^† · Garenoxacin · Gemifloxacin · Moxifloxacin · Gatifloxacin^‡ · Sitafloxacin · Trovafloxacin^‡/Alatrofloxacin^‡ · Prulifloxacin

Veterinary	Danofloxacin · Difloxacin · Enrofloxacin · Ibafloxacin · Marbofloxacin · Orbifloxacin · Pradofloxacin · Sarafloxacin

Related agents (DG)	Aminocoumarins: Novobiocin

Anaerobic DNA
inhibitors

Nitro- imidazole derivatives	Metronidazole^# · Tinidazole · Ornidazole

Nitrofuran derivatives	Nitrofurantoin^# · Nifurtoinol

RNA synthesis

Rifamycins/
RNA polymerase

Rifampicin · Rifabutin · Rifapentine · Rifaximin

^#WHO-EM. ^‡Withdrawn from market. CLINICAL TRIALS: ^†Phase III. ^§Never to phase III

Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)

Alveolate

Apicomplexa

Conoidasida/
(Coccidiostats)

Cryptosporidiosis	thiazole (Nitazoxanide)

Isosporiasis	Co-trimoxazole^#

Toxoplasmosis	Pyrimethamine • Sulfadiazine

Aconoidasida

Malaria

Hemozoin
inhibitors

Qs: Amino-	4-Aminoquinoline (Amodiaquine^#, Chloroquine^#, Hydroxychloroquine) • 8-Aminoquinoline (Primaquine^#, Pamaquine)

Qs: Methanol-	Mefloquine^# • Quinine^# • Quinidine

Other	phenanthrene methanol (Halofantrine) • amyl alcohol (Lumefantrine^#)

Antifolates

DRIs	2,4-Diaminopyrimidines (Pyrimethamine^#) • biguanides (Proguanil^#, Cycloguanil, Chlorproguanil)

DSIs	Sulfadoxine^# Sulfamethoxypyrazine

Sesquiterpene lactones

Artemisinin (Artemether^#, Artesunate^#, Artenimol, Arteether/Artemotil, Dihydroartemisinin)

Other

aminoacridine (Quinacrine) • ubiquinone analogue (Atovaquone) • tetracycline (Doxycycline^#)

Fixed-dose ACTs

Coartem • Artequin / ASMQ • ASAQ / Arsucam • Duo-Cotecxin (Artekin) • Ariplus • Co-Arinate • CDA

Other fixed-dose
combination therapies

Fansidar • Fansimef • Malarone • Lapdap

Babesiosis

Clindamycin

Ciliophora

Balantidiasis: Tetracycline

Heterokont

Blastocystosis: Metronidazole

^#WHO-EM. ^‡Withdrawn from market. CLINICAL TRIALS: ^†Phase III. ^§Never to phase III
see also diseases

This article about a heterocyclic compound is a stub. You can help Wikipedia by expanding it.

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