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Schwannoma
	Classification and external resources
	; Schwannoma
ICD-O:	M9560/0
DiseasesDB	33713
MeSH	D009442

A schwannoma (also known as an "Acoustic neuroma,"^[1] "Neurilemmoma,"^[2]^:621 "Neurinoma,"^[1] "Neurolemmoma,"^[1] and "Schwann cell tumor"^[1]) is a benign nerve sheath tumor composed of Schwann cells, which normally produce the insulating myelin sheath covering peripheral nerves.

Schwannomas are very homogeneous tumors, consisting only of Schwann cells. The tumor cells always stay on the outside of the nerve, but the tumor itself may either push the nerve aside and/or up against a bony structure (thereby possibly causing damage). Schwannomas are relatively slow growing. For reasons not yet understood, schwannomas are mostly benign and less than 1% become malignant, degenerating into a form of cancer known as neurofibrosarcoma.

Schwannomas can arise from a genetic disorder called neurofibromatosis. They are universally S-100 positive.

Schwannomas can be removed surgically, but can then recur.

[edit] Additional images

	Subcutaneous schwannoma

[edit] References

^ ^a ^b ^c ^d Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.
^ James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

[edit] See also

Neurofibroma
Vestibular schwannoma (Acoustic neuroma)

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[Bolognia-0] Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. ISBN 1-4160-2999-0.

[Andrews-1] James, William; Berger, Timothy; Elston, Dirk (2005). Andrews' Diseases of the Skin: Clinical Dermatology. (10th ed.). Saunders. ISBN 0-7216-2921-0.

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