Monobactams are beta-lactam compounds wherein the beta-lactam ring is alone and not fused to another ring (in contrast to most other beta-lactams, which have at least two rings). They work only against Gram-negative bacteria.[citation needed]
The only commercially available monobactam antibiotic is aztreonam.
Other examples of monobactams are tigemonam,[1] nocardicin A, and tabtoxin.
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