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 Mepivacaine hydrochloride N.F.
Mepivacaine hydrochloride N.F.
medicalcorps.org
 
Mepivacaine
Systematic (IUPAC) name
(RS)-N-(2,6-dimethylphenyl)- 1-methyl-piperidine-2-carboxamide
Identifiers
CAS number 96-88-8
ATC code N01BB03
PubChem 4062
DrugBank APRD01094
Chemical data
Formula C15H22N2O 
Mol. mass 246.348 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C, use w/ caution, may cause fetal bradycardia

Legal status
Routes  ?


Mepivacaine (pronounced /mɛˈpɪvəkeɪn/) is a local anesthetic[1] of the amino amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in any infiltration and regional anesthesia.

It is available as a racemate.[2]

[edit] References

  1. ^ Porto GG, Vasconcelos BC, Gomes AC, Albert D (January 2007). "Evaluation of lidocaine and mepivacaine for inferior third molar surgery". Med Oral Patol Oral Cir Bucal 12 (1): E60–4. PMID 17195831. http://www.medicinaoral.com/medoralfree01/v12i1/medoralv12i1p60.pdf. 
  2. ^ Burm AG, Cohen IM, van Kleef JW, Vletter AA, Olieman W, Groen K (January 1997). "Pharmacokinetics of the enantiomers of mepivacaine after intravenous administration of the racemate in volunteers". Anesth. Analg. 84 (1): 85–9. PMID 8989005. http://www.anesthesia-analgesia.org/cgi/pmidlookup?view=long&pmid=8989005. 

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