Manuel da Luz Afonso (Loulé, 31 January 1917 - 15 October 2000) was a Portuguese football manager.

He was the Head of the Football Departament of Benfica, during their 1960's Golden Era, when he was called to take office of Portugal national football team, in 1964, as "seleccionador" ("the selecter"), while Otto Glória would be the coach. That means Manuel da Luz Afonso would be choosing the players but wouldn't not be the coach in charge of the squad. They took office at 15 November 1964, in a 2–1 win over Spain, in a friendly match. It was the promising start to the successful campaign Portugal had in the way to the 1966 World Cup finals, in England. Portugal achieved the qualification for the first time, eliminating world's vice-champions Czechoslovakia. Portugal went to reach the 3 rd place at the World Cup finals.

Manuel da Luz Afonso left the National Team following the 1–2 loss to Sweden, at 13 November 1966, in a European Championship qualifier. He left the Portuguese squad after 20 matches, with 15 wins, 2 ties and 3 defeats, still the best record ever for his country.

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