MSK may refer to the following:

• Modern Sports Karate, a sports-fight martial art
• Memorial Sloan-Kettering, Hospital
• Minimum-shift keying (or similar Gaussian minimum shift keying), a type of radio modulation
• Codename for Moscow Time
• Medvedev-Sponheuer-Karnik seismic intensity scale (MSK-64)
• Musculoskeletal
• Museum voor Schone Kunsten (Museum of Fine Arts), Ghent, Belgium
• Mohammad Sidique Khan one of the men responsible for the 7 July 2005 London bombings
• Marske railway station, England; National Rail station code MSK
• Master Session Key, used in the Extensible Authentication Protocol (EAP)
• MySims Kingdom, a video game for the Wii and Nintendo DS

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