MMI may refer to: - 2001 in Roman numerals
- MMI Preparatory School, a college preparatory school in Freeland, Pennsylvania, United States
- Madison Media Institute, a college of media arts located in Madison, Wisconsin, United States
- Man-machine interaction, the study of interaction between people (users) and computers
- Man-machine interface or user interface, the "layer" that separates a human that is operating a machine from the machine itself
- Mind-machine interface or brain-computer interface, connecting the human or animal brain to digital equipment
- Manufacturers Mutual Insurance, a former Australian insurance company, now called Allianz Australia
- Marina Militare Italiana, the Italian Navy
- Marymount International School of Rome, a private Catholic school in Rome, Italy
- Maximum mutual information criterion, a statistical estimation method, which is an alternative to the widely used maximum likelihood estimation
- McMinn County Airport (FAA location identification code)
- Modified Mercalli intensity scale, an earthquake intensity measure
- Modigliani-Miller theorem proposition I, a theory in financial economics
- Modular multiplicative inverse
- Monolithic Memories, Inc. (1969-1987), an American semiconductor manufacturer
- Multi Media Interface, an in-car interface system developed by Audi
- Multiple Mini Interview, is an interview method to assess soft-skills
- W3C MMI (Multimodal Interaction Activity), an initiative of the W3C consortium
- Maximum medical improvement
- Miss May I, a band
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