Sinusoid of a rat liver with fenestrated endothelial cells. Fenestrae are approx 100 nm diameter, and the sinusoidal width 5 µm. Scanning electron micrograph by Robin Fraser, University of Otago.

A single lobule of the liver of a pig. X 60.

A liver sinusoid is a type of sinusoidal blood vessel (with fenestrated, discontinuous endothelium) that serve as a location for the oxygen-rich blood from the hepatic artery and the nutrient-rich blood from the portal vein.^[1]

Hepatocytes are separated from the sinusoids by the Space of Disse.

Liver sinusoids are equipped with Kupffer cells that can take up and destroy foreign material such as bacteria entering the sinusoids.

Human liver sinusoid

[edit] References

1. ^ SIU SOM Histology GI

[edit] External links

• Web page about the liver from the Christchurch School of Medicine
• UIUC Histology Subject 589
• Histology at BU 15504loa - "Liver, Gall Bladder, and Pancreas: liver, classic lobule"
• Histology at BU 22103loa - "Ultrastructure of the Cell: hepatocytes and sinusoids, sinusoid and space of Disse"
• Histology at anhb.uwa.edu.au

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