| Year | Bull | Issuer | Description |
| 1059 | In Nomine Domini ("In the name of the Lord") | Nicholas II | Establishing cardinal-bishops as the sole electors of the pope[1] |
| 1079 | Libertas ecclesiae ("The liberty of the Church") | Gregory VII | |
| 1079 | Antiqua sanctorum patrum | Gregory VII | Granted the church of Lyon primacy over the churches of Gaul |
| c. 1120 | Sicut Judaeis ("Thus to the Jews") | Callixtus II | Provides protection for the Jews who suffered from the hands of the participants in the First Crusade.[2] |
| 1136 (July 7) | Ex commisso nobis | Innocent II | Bull of Gniezno |
| 1139 (March 29) | Omne Datum Optimum | Innocent II | Endorses the Knights Templar. |
| 1144 | Milites Templi ("Soldiers of the Temple") | Celestine II | Provides clergy protection to the Knights Templar and encourages contributions to their cause. |
| 1145 | Militia Dei ("Soldiers of God") | Eugene III | Allows the Knights Templar to take tithes and burial fees and to bury their dead in their own cemeteries. |
| 1145 (December 1) | Quantum praedecessores ("How much did our predecessors") | Eugene III | Calls for the Second Crusade. |
| 1155 | Laudabiliter ("Laudably") | Adrian IV | Gives the English King Henry II lordship over Ireland. |
| 1184 | Ad Abolendam | Lucius III | Condemns heresy, and lists some punishments (though stops short of death). |
| 1187 (October 29) | Audita tremendi ("Hearing what terrible...") | Gregory VIII | Calls for the Third Crusade. |
| 1192 | Cum universi | Celestine III | |
| 1198 | Post Miserabile | Innocent III | Calls for the Fourth Crusade.[3] |
| 1199 (February 19) | | Innocent III | Assigns the uniform of a white tunic with a black cross to the Teutonic Knights. |
| 1205 | Etsi non displaceat | Innocent III | |
| 1213 | Quia maior | Innocent III | Calls for the Fifth Crusade. |
| 1216 (December) | Religiosam vitam ("The religious life") | Honorius III | Established the Dominican Order |
| 1218 | In generali concilio | Honorius III | |
| 1219 | Super speculam | Honorius III | |
| 1223 (November 29) | Solet annuere | Honorius III | Approves the Rule of St. Francis. |
| 1231 (April 13) | Parens scientarum ("The Mother of Sciences") | Gregory IX | Guarantees the independence of the University of Paris. |
| 1232 (February 8) | Ille humani generis | Gregory IX | |
| 1233 (June 13) | Vox Rama ("A voice in Ramah..") | Gregory IX | Condemns Satanic meetings held in Germany. It warns that Satan in these meetings can appear in form of animals like black cats, gooses, toads or like a thin, pale man.[4] | |
| 1233 | Etsi Judaeorum | Gregory IX | |
| 1233 | Licet ad capiendos | Gregory IX | |
| 1235 | Cum hora undecima ("Since the eleventh hour") | Gregory IX | First bull authorizing pagan friars to preach to pagan nations[5] |
| 1239 | Si vera sunt ("If they are true") | Gregory IX | |
| 1245 (March 5) | Dei patris immensa ("God the Father's immense...") | Innocent IV | Exposition of the Christian faith, and urged Mongols to accept baptism[6] |
| 1245 (March 13) | Cum non solum ("With not only...") | Innocent IV | Appeal to the Mongols to desist from attacking Christians and other nations, and an enquiry as to their future intentions.[6] Innocent expresses desire for peace (possibly unaware that in the Mongol vocabulary, "peace" is a synonym for "subjection")[7] |
| 1245 (late March) | Cum simus super | Innocent IV | Letter addressed to multiple prelates and 'Christians of the East' which affirmed the primacy of the Roman Church and urged ecclesiastical unity[8] |
| 1247 | Lachrymabilem Judaeorum | Innocent IV | |
| 1248 (November 22) | Viam agnoscere veritatis | Innocent IV | Letter addressed to Baiju, king of the Mongols, in response to his embassy. |
| 1252 (May 15) | Ad exstirpanda ("For the elimination") | Innocent IV | Authorizes the use of torture for eliciting confessions from heretics during the Inquisition and executing relapsed heretics by burning them alive. |
| 1254 (October 6) | Querentes in agro | Innocent IV | |
| 1263/1264 | Exultavit cor nostrum ("Our heart has rejoiced") | Urban IV | Letter from Urban to Hulagu, discussing the arrival of Hulagu's (uncredentialed) envoy John the Hungarian, cautiously welcoming, and announcing that William II of Agen, Latin Patriarch of Jerusalem, would be investigating further.[9] |
| 1264 | ? | Urban IV | Discussion of the Egyptian threat (no mention of Mongols)[9] |
| 1267 | Turbato corde | Clement IV | |
| 1274 | Ubi Periculum ("Where there is danger") | Gregory X | |
| 1296 (January 20) | Redemptor mundi ("Redeemer of the world") | Boniface VIII | Named James II of Aragon as standardbearer, captain-general, and admiral of the Roman Church. |
| 1296 (February 25) | Clericis Laicos ("Lay clerics") | Boniface VIII | Excommunicates all members of the clergy who, without authorization from the Holy See, pay to laymen any part of their income or the revenue of the Church, and all rulers who receive such payments. |
| 1297 | Super rege et regina ("About king and queen") | Boniface VIII | Bestowed on James II of Aragon the Kingdom of Sardinia and Corsica. |
| 1299 (27 June) | Scimus, Fili ("We know, my son") | Boniface VIII | Declared King Edward I of England's occupation of Scotland to be illegal. |
| 1299 | De Sepulturis | Boniface VIII | Prohibits the dismembering and boiling of the bodies so that the bones, separated from the flesh, may be carried for burial in their own countries. |
| 1300 (22 February) | Antiquorum fida relatio | Boniface VIII | Reinstates the Jubilee Years, granting indulgence during those years for those who fulfill various conditions |
| 1302 (November 18) | Unam Sanctam ("The One Holy") | Boniface VIII | Declares that there is no salvation outside the Church (Extra Ecclesiam nulla salus), and that the Church must remain united. |
| 1307 (November 22) | Pastoralis praeminentiæ | Clement V | Orders the arrest of the Knights Templar and the confiscation of their possessions. |
| 1307 (23 July) | Rex regnum | Clement V | Nominates seven Franciscans to act as papal suffragens in China[10] |
| 1308 | Fasciens misericordiam | Clement V | Sets out the procedure to prosecute the Knights Templar. |
| 1308 (August 12) | Regnans in coelis ("Reigning in heaven") | Clement V | Convenes the Council of Vienne to discuss the Knights Templar. |
| 1310 (April 4) | Alma mater ("A nurturing mother") | Clement V | Postpones the opening of the Council of Vienne until 1 Oct., 1311, on account of the investigation of the Templars that was not yet finished. |
| 1312 (March 22) | Vox in excelso ("A voice from on high") | Clement V | Disbands the Knights Templar. |
| 1312 (May 2) | Ad providam | Clement V | Grants the bulk of Templar property on to the Knights Hospitallers. |
| 1312 (May 6) | Considerantes dudum | Clement V | |
| 1312 (May 16) | Nuper in concilio | Clement V | |
| 1312 (December 18) | Licet dudum | Clement V | |
| 1312 (December 31) | Dudum in generali concilio | Clement V | |
| 1313 (January 13) | Licet pridem | Clement V | |
| 1317 | Sane Considerante | John XXII | |
| 1318 (April 1) | Redemptor noster ("Our redeemer") | John XXII | Withdrew the Mongol Ilkhan's dominions and 'India' from the archdiocese of Khanbaligh, transferring to a Dominican province |
| 1323 | Cum inter nonnullos | John XXI | Definition on the Poverty of Christ and the Apostles |
| 1336 | Benedictus Deus | Benedict XII | |
| 1348 september 26 | Quamvis Perfidiam | Clement VI | |
| 1350 | cum natura humana | Clement VI | |
| 1425 | | Martin V | Foundation of the Université Catholique de Louvain |
| 1435 | Sicut Dudum | Eugene IV | Forbidding the slavery of black natives in the Canary Islands by Spanish slave traders |
| 1439 (July 6) | Laetantur Coeli | Eugene IV | |
| 1451 (January 7) | | Nicholas V | Foundation of the University of Glasgow [1] |
| 1452 (June 18) | Dum diversas | Nicholas V | Authorizes Afonso V of Portugal to reduce any Muslims, pagans and other unbelievers to perpetual slavery. |
| 1455 (January 8) | Romanus Pontifex ("The Roman pontiff") | Nicholas V | Sanctifies the seizure of non-Christian lands discovered during the Age of Discovery and encourages the enslavement of natives. |
| 1456 (June 20) | Cum hiis superioribus annis and is titled "Bulla Turcorum" | Calixtus III | Announces the Fall of Constantinople and seeks funding for another crusade against the Turks. |
| 1470 (April 19) | Ineffabilis providentia ("Ineffable Providence") | Paul II | |
| 1478 (November 1) | Exigit sinceræ devotionis | Sixtus IV | Creates the Spanish Inquisition. |
| 1481 (June 21) | Aeterni regis | Sixtus IV | Confirms the Treaty of Alcáçovas. |
| 1484 (December 5) | Summis desiderantes | Innocent VIII | Condemns an alleged outbreak of witchcraft and heresy in the region of the Rhine River valley, and deputizes Heinrich Kramer and Jacob Sprenger as inquisitors to root out alleged witchcraft in Germany. |
| 1493 (May 4) | Inter caetera ("Among the other") | Alexander VI | Divides the New World between Spain and Portugal. |
| 1493 (June 25) | Piis Fidelium | Alexander VI | Grants Spain vicarial power to appoint missionaries to the Indies. |
| 1513 (December 19) | Apostolici Regiminis | Leo X | Concerning immortality of the soul. |
| 1514 | Supernæ | Leo X | Declares that the cardinals in a body should come immediately after the pope and precede all others in the church. |
| 1520 (June 15) | Exsurge Domine ("Arise, O Lord") | Leo X | Demands that Martin Luther retract 41 of his 95 theses, as well as other specified errors, within sixty days of its publication in neighbouring regions to Saxony. |
| 1521 (January 3) | Decet Romanum Pontificem ("[It] befits [the] Roman Pontiff") | Leo X | Excommunicates Martin Luther. |
| 1537 (May 29) | Sublimus Dei | Paul III | Forbids the enslavement of the indigenous peoples of the Americas. |
| 1540 (September 27) | Regimini militantis ecclesiae ("To the Government of the Church Militant") | Paul III | Approves the formation of the Society of Jesus. |
| 1543 (March 14) | Injunctum nobis | Paul III | |
| 1550 (July 21) | Exposcit debitum ("The Duty demands") | Julius III | Second and final approval of the Society of Jesus |
| 1553 (April 28) | Divina disponente clementia ("So predisposed by the divine clemency") | Julius III | Create Shimun VIII Yohannan Sulaqa the first patriarch of the Chaldean Catholic Church. |
| 1555 (July 14) | Cum nimis absurdum ("Since it is absurd") | Paul IV | Places religious and economic restrictions on Jews in the Papal States. |
| 1559 (February 15) | Cum ex apostolatus officio | Paul IV | Confirms that only Catholics can be elected Popes. |
| 1564 (January 26) | Benedictus Deus | Pius IV | Ratified all decrees and definitions of the Council of Trent. It enjoins strict obedience upon all Catholics and forbids, under pain of excommunication, all unauthorized interpretation. |
| 1565 (January 17) | Æquum reputamus | Pius V | |
| 1570 (February 25) | Regnans in Excelsis ("Ruling from on high) | Pius V | Declares Elizabeth I of England a heretic and releases her subjects from any allegiance to her. |
| 1570 (July 14) | Quo Primum | Pius V | Describes the method use to reform the Roman rite, promulgates the Missal of Pius V (Tridentine rite, and abrogates any other rite which cannot demonstrate two hundred year of continuous use |
| 1582 (February 24) | Inter gravissimas ("Among the most important") | Gregory XIII | Establishes the Gregorian calendar. |
| 1586 (January) | Coeli et terrae ("The heavens and the lands") | Sixtus V | condemned "judicial astrology" as superstitious. |
| 1588 (February 11) | Immensa Aeterni Dei | Sixtus V | |
| 1653 (May 31) | Cum occasione | Innocent X | Condemns 5 Jansenist propositions. |
| 1665 | Ad Sacram | Alexander VII | |
| 1692 | Romanum decet Pontificem | Innocent XII | Abolished the office of Cardinal-Nephew |
| 1713 | Unigenitus ("The only-begotten") | Clement XI | Condemns Jansenism. |
| 1738 | In eminenti apostolatus specula ("in the high watchtower of the Apostolate") | Clement XII | Bans Catholics from becoming Freemasons. |
| 1773 | Dominus ac Redemptor Noster ("Our Master and Redeemer") | Clement XIV | Permanently and irrevocably suppressing the Society of Jesus. |
| 1814 | Sollicitudo omnium ecclesiarum ("The care of all the churches") | Pius VII | Reestablishes the Society of Jesus. |
| 1824 | Quod divina sapientia ("what divine wisdom") | Leo XII | Restructures education in the Papal States under ecclesiastical supervision |
| 1850 (September 29) | Universalis Ecclesiae ("of the Universal Church") | Pius IX | Recreates the Roman Catholic hierarchy in England. |
| 1866 (July 12) | Reversurus ("to came back") | Pius IX | Extends to the Armenian Catholic Church the Western provisions about appointment of bishops |
| 1868 (June 29) | Aeterni Patris ("of the Eternal Father") | Pius IX | Summons First Vatican Council. |
| 1869 (October 12) | Apostolicæ Sedis Moderationi ("to the spirit of the Apostolic See") | Pius IX | Regulates the system of censures and reservations in the Catholic Church. |
| 1871 | Pastor aeternus ("The eternal shepherd") | Pius IX | Defines papal infallibility. |
| 1880 (July 13) | Dolemus inter alia ("Among other things, we lament") | Leo XIII | |
| 1896 | Apostolicae Curae ("of the Apostolic care") | Leo XIII | Declares all Anglican Holy Orders null and void. |
| 1910 | Quam singulari ("how special") | Pius X | Allows the admittance of Communion to children who have reached the age of reason (about seven years old). |
| 1950 (November 1) | Munificentissimus Deus ("The most bountiful God") | Pius XII | Defines the dogma of the Assumption of Mary. |
| 1961 (December 25) | Humanae salutis ("of human salvation") | John XXIII | Summons Second Vatican Council. |
| 1965 (November 18) | Dei Verbum ("Word of God") | Paul VI | |
| 1998 (November 29) | Incarnationis mysterium ("The mystery of the Incarnation") | John Paul II | Indiction of the Great Jubilee of 2000 |
1145: First formal Papal Bull of Crusade (‘Bulla cruciata’ - calling on France to restore the Holy Land to Christendom) issued by Eugenius III, together with ‘Quantum prædecessors’
1226: "Solet annuere" November 29, 1226 [Bull approving the Rule of St. Francis] Pope Honorius III
1247: Bull :Quae Honorem Conditoris Omnium (Whatever Is for the Honor of the Creator of All) October 1, 1247
