| Train Name | Railroad | Train Endpoints | Operated |
| AB-Klassiker | AB | Appenzell – Wasserauen | present |
| Aqualino[1] | RhB | Scuol-Tarasp – Chur – Disentis/Muster | present |
| Bernina Express | RhB | Chur – St. Moritz – Tirano | present |
| CNL Apus | CNL | Amsterdam (Centraal) – Bellinzona – Milan (Central) | present |
| CNL Aurora | CNL | Zurich (Hauptbahnhof) – Copenhagen (Central) | present |
| CNL Berliner | CNL | Zurich (Hauptbahnhof) – Berlin (Hauptbahnhof) | present |
| CNL Komet | CNL | Zurich (Hauptbahnhof) – Hamburg (Hauptbahnhof) | present |
| CNL Orion | CNL | Basel – Dresden (Hauptbahnhof) – Prague (Main) | present |
| CNL Pegasus | CNL | Amsterdam (Centraal) – Zurich (Hauptbahnhof) – Brig | present |
| CNL Semper | CNL | Zurich (Hauptbahnhof) – Dresden (Hauptbahnhof) | present |
| EC Borromeo | Cisalpino | Basel – Bern (Main) – Milan (Central) | present |
| EC Canaletto | Cisalpino | Zurich (Hauptbahnhof) – Venice (Santa Lucia) | present |
| EC Cinque Terre | Cisalpino | Zurich (Hauptbahnhof) – La Spezia | present |
| EC Iris | SNCB, CFL, SNCF, SBB-CFF-FFS | Brussels (Midi/Zuid) – Strasbourg – Chur | present |
| EC Jean Monet | SNCB, CFL, SNCF | Brussels (Midi/Zuid) – Strasbourg – Basel | present |
| EC Kaiserin Elisabeth | SBB-CFF-FFS, ÖBB | Zurich (Hauptbahnhof) – Salzburg | present |
| EC Lemano | Cisalpino | Geneva – Milan (Central) | present |
| EC Maria Theresia | SBB-CFF-FFS, ÖBB | Zurich (Hauptbahnhof) – Vienna (Südbahnhof) | present |
| EC Monte Rosa | Cisalpino | Geneva – Milan (Central) | present |
| EC Transalpin | SBB-CFF-FFS, ÖBB | Basel – Vienna (Südbahnhof) | present |
| EC Vall D’Ossola | Cisalpino | Basel – Bern (Main) – Milan (Central) | present |
| EC Vallese | Cisalpino | Geneva – Milan (Central) | present |
| EC Vauban | SNCB, CFL, SNCF, SBB-CFF-FFS | Brussels (Midi/Zuid) – Strasbourg – Brig | present |
| EC Verbano | Cisalpino | Basel – Bern (Main) – Milan (Central) | present |
| EN Roma | SBB-CFF-FFS, Trenitalia | Zurich (Hauptbahnhof) – Venice (Santa Lucia)
Zurich (Hauptbahnhof) – Rome (Termini) | present |
| EN Wiener Walzer | SBB-CFF-FFS, ÖBB, ČD, MÁV | Zurich (Hauptbahnhof) – Prague (Main)
Zurich (Hauptbahnhof) – Vienna (Südbahnhof) – Budapest Nyugati | present |
| EN Zürichsee | SBB-CFF-FFS, ÖBB, SŽ, HŽ, ŽS | Zurich (Hauptbahnhof) – Ljubljana (Main) – Zagreb – Beograd | present |
| Engadin Star[2] | RhB | Landquart – St. Moritz | present |
| Glacier Express | MGB, RhB | Zermatt – St. Moritz | present |
| Glarner Sprinter | SBB-CFF-FFS | Zurich (Hauptbahnhof) – Linthal | present |
| GoldenPass Line | Zentralbahn, BLS, MOB | Lucerne – Interlaken – Zweisimmen – Montreux | present |
| Heidi Express | RhB | Chur – St. Moritz – Tirano | present |
| IC Brianza | Cisalpino | Bellinzona – Milan (Central) | present |
| IC Insubria | SBB-CFF-FFS, Trenitalia | Stuttgart (Hauptbahnhof) – Zurich (Hauptbahnhof) – Milan (Central) | present |
| IC Mediolanum | SBB-CFF-FFS, Trenitalia | Basel – Lucerne – Milan (Central) | present |
| IC Monte Ceneri | Cisalpino | Zurich (Hauptbahnhof) – Milan (Central) | present |
| IC Riviera dei Fiori | Cisalpino | Basel – Lucerne – Genova – Nice | present |
| IC Teodolina | Cisalpino | Zurich (Hauptbahnhof) – Milan (Central) | present |
| IC Ticino | SBB-CFF-FFS, Trenitalia | Basel – Lucerne – Milan (Central) | present |
| IC Tiziano | SBB-CFF-FFS, Trenitalia | Basel – Lucerne – Milan (Central) | present |
| IC Verdi | SBB-CFF-FFS, Trenitalia | Basel – Lucerne – Milan (Central) | present |
| RE Lötschberg[3] | BLS | Spiez – Kandersteg – Goppenstein (Lötschental) – Brig | present |
| Rheingold Express | | Basel – Hook of Holland | 1934 – 1987 |
| Rheintal Express | SBB-CFF-FFS | St. Gallen – Chur | present |
| Train des Vignes | SBB-CFF-FFS | Vevey – Puidoux-Chexbres | present |
| Train du Chocolat[4] | TPF | Montreux – Gruyères – Broc | present |
| Trenhotel Pau Casals | Elipsos | Zurich (Hauptbahnhof) – Barcelona (Estació de França) | present |
| Trenino della neve | RhB | St. Moritz – Tirano | present |
| Train Fondue | TPF | (Montreux) – Montbovon – Bulle | present |
| Voralpen Express | Südostbahn, SBB-CFF-FFS | Lucerne – Romanshorn | present |
