County
| FIPS Code [1] | County seat [2] | Established [2] | Origin
| Etymology
| Population
| Area
| Map
|
| Abbeville County | 001 | Abbeville | 1785 | Ninety-Six District | Abbeville France | &0000000000026167.00000026,167 | &0000000000000511.000000511 sq mi (&0000000000001323.0000001,323 km2) |  |
| Aiken County | 003 | Aiken | 1871 | Barnwell, Edgefield, Lexington, and Orangeburg | William Aiken | &0000000000142552.000000142,552 | &0000000000001080.0000001,080 sq mi (&0000000000002797.0000002,797 km2) |  |
| Allendale County | 005 | Allendale | 1919 | Barnwell and Hampton | Allendale family | &0000000000011211.00000011,211 | &0000000000000413.000000413 sq mi (&0000000000001070.0000001,070 km2) |  |
| Anderson County | 007 | Anderson | 1826 | Pendleton District | Robert Anderson | &0000000000165740.000000165,740 | &0000000000000757.000000757 sq mi (&0000000000001961.0000001,961 km2) |  |
| Bamberg County | 009 | Bamberg | 1897 | Barnwell | Francis Marion Bamberg | &0000000000016658.00000016,658 | &0000000000000395.000000395 sq mi (&0000000000001023.0000001,023 km2) |  |
| Barnwell County | 011 | Barnwell | 1798 | Orangeburg | Barnwell family | &0000000000023478.00000023,478 | &0000000000000557.000000557 sq mi (&0000000000001443.0000001,443 km2) |  |
| Beaufort County | 013 | Beaufort | 1764 | 1769 Judicial District | Duke of Beaufort | &0000000000120937.000000120,937 | &0000000000000923.000000923 sq mi (&0000000000002391.0000002,391 km2) |  |
| Berkeley County | 015 | Moncks Corner | 1882 | Charleston | William Berkeley | &0000000000142651.000000142,651 | &0000000000001228.0000001,228 sq mi (&0000000000003181.0000003,181 km2) |  |
| Calhoun County | 017 | St. Matthews | 1908 | Lexington and Orangeburg | John C. Calhoun | &0000000000015185.00000015,185 | &0000000000000392.000000392 sq mi (&0000000000001015.0000001,015 km2) |  |
| Charleston County | 019 | Charleston | 1769 | 1769 Judicial District | Charles II of England | &0000000000309969.000000309,969 | &0000000000001358.0000001,358 sq mi (&0000000000003517.0000003,517 km2) |  |
| Cherokee County | 021 | Gaffney | 1897 | Spartanburg, Union, and York | Cherokee Native Americans | &0000000000052327.00000052,327 | &0000000000000397.000000397 sq mi (&0000000000001028.0000001,028 km2) |  |
| Chester County | 023 | Chester | 1785 | Camden District | Chester, Pennsylvania | &0000000000034068.00000034,068 | &0000000000000586.000000586 sq mi (&0000000000001518.0000001,518 km2) |  |
| Chesterfield County | 025 | Chesterfield | 1798 | Cheraws District | Philip Dormer Stanhope, 4th Earl of Chesterfield | &0000000000042768.00000042,768 | &0000000000000806.000000806 sq mi (&0000000000002088.0000002,088 km2) |  |
| Clarendon County | 027 | Manning | 1855 | Sumter | Edward Hyde, 1st Earl of Clarendon | &0000000000032502.00000032,502 | &0000000000000696.000000696 sq mi (&0000000000001803.0000001,803 km2) |  |
| Colleton County | 029 | Walterboro | 1800 | Charleston | John Colleton | &0000000000038264.00000038,264 | &0000000000001133.0000001,133 sq mi (&0000000000002934.0000002,934 km2) |  |
| Darlington County | 031 | Darlington | 1785 | Cheraws District | Darlington, England | &0000000000067394.00000067,394 | &0000000000000567.000000567 sq mi (&0000000000001469.0000001,469 km2) |  |
| Dillon County | 033 | Dillon | 1910 | Marlboro | J.W. Dillon | &0000000000030722.00000030,722 | &0000000000000407.000000407 sq mi (&0000000000001054.0000001,054 km2) |  |
| Dorchester County | 035 | St. George | 1868 | Berkeley and Colleton | Dorchester, Massachusetts | &0000000000096413.00000096,413 | &0000000000000577.000000577 sq mi (&0000000000001494.0000001,494 km2) |  |
| Edgefield County | 037 | Edgefield | 1785 | Ninety-Six District | located on the edge of the state | &0000000000024595.00000024,595 | &0000000000000507.000000507 sq mi (&0000000000001313.0000001,313 km2) |  |
| Fairfield County | 039 | Winnsboro | 1785 | Camden District | fair fields | &0000000000023454.00000023,454 | &0000000000000710.000000710 sq mi (&0000000000001839.0000001,839 km2) |  |
| Florence County | 041 | Florence | 1888 | Clarendon, Darlington, Marion, and Williamsburg | Florence Harllee | &0000000000125761.000000125,761 | &0000000000000804.000000804 sq mi (&0000000000002082.0000002,082 km2) |  |
| Georgetown County | 043 | Georgetown | 1769 | 1769 Judicial District | George II of Great Britain | &0000000000055797.00000055,797 | &0000000000001035.0000001,035 sq mi (&0000000000002681.0000002,681 km2) |  |
| Greenville County | 045 | Greenville | 1798 | Washington District | Nathanial Greene | &0000000000395357.000000395,357 | &0000000000000795.000000795 sq mi (&0000000000002059.0000002,059 km2) |  |
| Greenwood County | 047 | Greenwood | 1897 | Abbeville and Edgefield | Greenwood Plantation | &0000000000066271.00000066,271 | &0000000000000463.000000463 sq mi (&0000000000001199.0000001,199 km2) |  |
| Hampton County | 049 | Hampton | 1787 | Beaufort | Wade Hampton | &0000000000021386.00000021,386 | &0000000000000563.000000563 sq mi (&0000000000001458.0000001,458 km2) |  |
| Horry County | 051 | Conway | 1801 | Georgetown | Revolutionary War general Peter Horry | &0000000000217608.000000217,608 | &0000000000001255.0000001,255 sq mi (&0000000000003250.0000003,250 km2) |  |
| Jasper County | 053 | Ridgeland | 1912 | Beaufort and Hampton | William Jasper | &0000000000020678.00000020,678 | &0000000000000700.000000700 sq mi (&0000000000001813.0000001,813 km2) |  |
| Kershaw County | 055 | Camden | 1798 | Claremont, Fairfield, Lancaster, and Richland | Joseph Kershaw | &0000000000052647.00000052,647 | &0000000000000740.000000740 sq mi (&0000000000001917.0000001,917 km2) |  |
| Lancaster County | 057 | Lancaster | 1798 | Camden District | Lancaster County, Pennsylvania | &0000000000061351.00000061,351 | &0000000000000555.000000555 sq mi (&0000000000001437.0000001,437 km2) |  |
| Laurens County | 059 | Laurens | 1785 | Ninety-Six District | Henry Laurens | &0000000000069567.00000069,567 | &0000000000000724.000000724 sq mi (&0000000000001875.0000001,875 km2) |  |
| Lee County | 061 | Bishopville | 1902 | Darlington, Kershaw, and Sumter | Robert E. Lee | &0000000000020119.00000020,119 | &0000000000000411.000000411 sq mi (&0000000000001064.0000001,064 km2) |  |
| Lexington County | 063 | Lexington | 1804 | Orangeburg | Battle of Lexington | &0000000000216014.000000216,014 | &0000000000000758.000000758 sq mi (&0000000000001963.0000001,963 km2) |  |
| Marion County | 065 | Marion | 1800 | Georgetown | Francis Marion | &0000000000035466.00000035,466 | &0000000000000494.000000494 sq mi (&0000000000001279.0000001,279 km2) |  |
| Marlboro County | 067 | Bennettsville | 1798 | Cheraws District | John Churchill, 1st Duke of Marlborough | &0000000000028818.00000028,818 | &0000000000000485.000000485 sq mi (&0000000000001256.0000001,256 km2) |  |
| McCormick County | 069 | McCormick | 1914 | Abbeville, Edgefield, and Greenwood | Cyrus McCormick | &0000000000009958.0000009,958 | &0000000000000394.000000394 sq mi (&0000000000001020.0000001,020 km2) |  |
| Newberry County | 071 | Newberry | 1785 | Ninety-Six District | unknown | &0000000000036108.00000036,108 | &0000000000000647.000000647 sq mi (&0000000000001676.0000001,676 km2) |  |
| Oconee County | 073 | Walhalla | 1868 | Pickens | Oconee Native Americans | &0000000000066215.00000066,215 | &0000000000000674.000000674 sq mi (&0000000000001746.0000001,746 km2) |  |
| Orangeburg County | 075 | Orangeburg | 1769 | 1769 Judicial District | William V of Orange | &0000000000091582.00000091,582 | &0000000000001128.0000001,128 sq mi (&0000000000002922.0000002,922 km2) |  |
| Pickens County | 077 | Pickens | 1826 | Pendleton District | Andrew Pickens | &0000000000110757.000000110,757 | &0000000000000512.000000512 sq mi (&0000000000001326.0000001,326 km2) |  |
| Richland County | 079 | Columbia | 1799 | Camden District | rich soil | &0000000000320677.000000320,677 | &0000000000000772.000000772 sq mi (&0000000000001999.0000001,999 km2) |  |
| Saluda County | 081 | Saluda | 1896 | Edgefield | Saluda River | &0000000000019181.00000019,181 | &0000000000000462.000000462 sq mi (&0000000000001197.0000001,197 km2) |  |
| Spartanburg County | 083 | Spartanburg | 1785 | Ninety-Six District | Spartan Regiment | &0000000000253791.000000253,791 | &0000000000000819.000000819 sq mi (&0000000000002121.0000002,121 km2) |  |
| Sumter County | 085 | Sumter | 1798 | Claremont, Clarendon, and Salem | Thomas Sumter | &0000000000104646.000000104,646 | &0000000000000682.000000682 sq mi (&0000000000001766.0000001,766 km2) |  |
| Union County | 087 | Union | 1798 | Ninety-Six District | Union Church | &0000000000029881.00000029,881 | &0000000000000516.000000516 sq mi (&0000000000001336.0000001,336 km2) |  |
| Williamsburg County | 089 | Kingstree | 1802 | Georgetown District | Prince William, Duke of Cumberland | &0000000000037217.00000037,217 | &0000000000000937.000000937 sq mi (&0000000000002427.0000002,427 km2) |  |
| York County | 091 | York | 1798 | Camden District | York County, Pennsylvania | &0000000000164614.000000164,614 | &0000000000000696.000000696 sq mi (&0000000000001803.0000001,803 km2) |  |