| Draft | Round | Pick | Player | Nationality | Pos | RS | PO |
| 1963 | 1 | 5 | Hampson, ArtArt Hampson |  Canada | D | | |
| 1964 | 1 | 4 | Bayes, RichieRichie Bayes | Canada | C | | |
| 1965 | 1 | 2 | Culligan, AndyAndy Culligan | Canada | | | |
| 1966 | 1 | 3 | Caffery, TerryTerry Caffery | Canada | C | 14 | 1 |
| 1967 | 1 | 7 | Tombari, BobBob Tombari | Canada | LW | | |
| 1968 | 1 | 9 | Marks, JohnJohn Marks | Canada | D | 657 | 57 |
| 1969 | 1 | 13 | Bordeleau, Jean-PierreJean-Pierre Bordeleau | Canada | RW | 519 | 48 |
| 1970 | 1 | 7 | Maloney, DanDan Maloney | Canada | LW | 131 | 10 |
| 1971 | 1 | 12 | Spring, DanDan Spring | Canada | F | | |
| 1972 | 1 | 13 | Russell, PhilPhil Russell | Canada | D | 504 | 39 |
| 1973 | 1 | 13 | Rota, DarcyDarcy Rota | Canada | LW | 448 | 28 |
| 1974 | 1 | 16 | Mulvey, GrantGrant Mulvey | Canada | RW | 574 | 42 |
| 1975 | 1 | 7 | Vaydik, GregoryGregory Vaydik | Canada | C | 5 | 0 |
| 1976 | 1 | 9 | Cloutier, RealReal Cloutier | Canada | RW | | |
| 1977 | 1 | 6 | Wilson, DouglasDouglas Wilson | Canada | D | 938 | 95 |
| 1978 | 1 | 10 | Higgins, TimTim Higgins | Canada | R | 358 | 39 |
| 1979 | 1 | 7 | Brown, KeithKeith Brown | Canada | D | 812 | 103 |
| 1980 | 1 | 3 | Savard, DenisDenis Savard | Canada | C | 881 | 131 |
| 1980 | 1 | 15 | Dupont, JeromeJerome Dupont | Canada | D | 201 | 20 |
| 1981 | 1 | 12 | Tanti, TonyTony Tanti | Canada | RW | 3 | 0 |
| 1982 | 1 | 7 | Yaremchuk, KenKen Yaremchuk | Canada | C | 188 | 19 |
| 1983 | 1 | 18 | Cassidy, BruceBruce Cassidy | Canada | D | 36 | 1 |
| 1984 | 1 | 3 | Olczyk, EdEd Olczyk |  USA | RW | 322 | 22 |
| 1985 | 1 | 11 | Manson, DaveDave Manson | Canada | D | 431 | 50 |
| 1986 | 1 | 14 | Sanipass, EverettEverett Sanipass | Canada | LW | 126 | 5 |
| 1987 | 1 | 8 | Waite, JimmyJimmy Waite | Canada | G | 58 | 0 |
| 1988 | 1 | 8 | Roenick, JeremyJeremy Roenick | USA | C | 524 | 82 |
| 1989 | 1 | 6 | Bennett, AdamAdam Bennett | Canada | D | 21 | 0 |
| 1990 | 1 | 16 | Dykhuis, KarlKarl Dykhuis | Canada | D | 18 | 0 |
| 1991 | 1 | 22 | McAmmond, DeanDean McAmmond | Canada | C | 154 | 3 |
| 1992 | 1 | 12 | Krivokrasov, SergeiSergei Krivokrasov |  Russia | RW | 225 | 21 |
| 1993 | 1 | 24 | Lecompte, EricEric Lecompte | Canada | LW | 0 | 0 |
| 1994 | 1 | 14 | Moreau, EthanEthan Moreau | Canada | LW | 210 | 6 |
| 1995 | 1 | 19 | Nabokov, DmitriDmitri Nabokov | Russia | RW | 25 | 0 |
| 1996 | N/A | | | | | | |
| 1997 | 1 | 13 | Cleary, DanielDaniel Cleary | Canada | RW | 41 | 0 |
| 1997 | 1 | 16 | Jones, TyTy Jones | USA | RW | 8 | 0 |
| 1998 | 1 | 8 | Bell, MarkMark Bell | Canada | LW | 339 | 5 |
| 1999 | 1 | 23 | McCarthy, SteveSteve McCarthy | Canada | LW | 134 | 0 |
| 2000 | 1 | 10 | Yakubov, MikhailMikhail Yakubov | Russia | C | 40 | 0 |
| 2000 | 1 | 11 | Vorobiev, PavelPavel Vorobiev |  Kazakhstan | RW | 57 | 0 |
| 2001 | 1 | 9 | Ruutu, TuomoTuomo Ruutu |  Finland | LW | 228 | 0 |
| 2001 | 1 | 29 | Munro, AdamAdam Munro | Canada | G | 17 | 0 |
| 2002 | 1 | 21 | Babchuk, AntonAnton Babchuk |  Ukraine | D | 22 | 0 |
| 2003 | 1 | 14 | Seabrook, BrentBrent Seabrook | Canada | D | 314 | 17 |
| 2004 | 1 | 3 | Barker, CamCam Barker | Canada | D | 149 | 17 |
| 2005 | 1 | 7 | Skille, JackJack Skille | USA | RW | 22 | 0 |
| 2006 | 1 | 3 | Toews, JonathanJonathan Toews | Canada | C | 146 | 17 |
| 2007 | 1 | 1 | Kane, PatrickPatrick Kane | USA | RW | 162 | 16 |
| 2008 | 1 | 11 | Beach, KyleKyle Beach | Canada | C | 0 | 0 |
| 2009 | 1 | 28 | Olsen, DylanDylan Olsen | Canada | D | 0 | 0 |
