Ligand may refer to:

• Ligand, an atom, ion, or functional group that donates one or more of its electrons through a coordinate covalent bond to one or more central atoms or ions
• Ligand (biochemistry), an extracellular substance that binds to receptors: 'guest' in host-guest chemistry
• Ligandome, the whole set of ligands in biological cells
• Ligand Pharmaceuticals, Inc. A Delaware corporation, based in San Diego, California.

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