Lagochilin Information & Lagochilin Links at HealthHaven.com

Lagochilin
IUPAC name	(6S,2R)-2,12-bis(hydroxymethyl)-12-(2-hydroxyethyl)-2,6,8-trimethylspiro[bicyc lo[4.4.0]decane-7,5'-oxolane]-3-ol
Identifiers
CAS number	23554-81-6
SMILES	C[C@@]1(CO)[C@@H](O)CC[C@@]2(C)[C@]([H])1CC[C@@H](C)[C@]32O[C@](CO)(CCO)CC3
Properties
Molecular formula	C20H36O5
Molar mass	356.495 g/mol
Appearance	Light grey crystalline solid
	Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
	Infobox references

Lagochilin is a bitter diterpene that forms a grey crystalline solid. It is found in various plants from the genus Lagochilus, most notably Lagochilus inebrians, and is thought to be responsible for the sedative, hypotensive and hemostatic effects of this plant.^[1]^[2]^[3]

[edit] References

^ Pulatova TP, Khazanovich RL. On the alkaloid content of some Lagochilus species and on the nature of lagochiline. (Russian) Aptechnoe Delo. 1962 Nov-Dec;6:29-32. PMID 13972488
^ Mavlyankulova ZI, Zainutdinov UN, Mukhamedkhanov SI, Leont'ev VD, Aslanov Kh.A, Khimiya Prirodnykh Soedinenii. 1980;1:46.
^ Chizhov, O. S.; Kessenikh, A. V.; Yakovlev, I. P.; Zolotarev, B. M.; Petukhov, V. A.; Zelinskii, N. D. (1969). "Structure of lagochilin". Tetrahedron Letters 17: 1361-1364.

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