Lactucin
IUPAC name	(3aR,4R,9aS,9bR)-4-Hydroxy-9-(hydroxymethyl)-6-methyl-3-methylene-4,5,9a,9b-tetrahydro-3aH-azuleno[5,4-d]furan-2,7-dione
Identifiers
CAS number	1891-29-8
PubChem	821383
SMILES	CC1=C2C(C3C(C(C1)O)C(=C)C(=O)O3)C(=CC2=O)CO
Properties
Molecular formula	C15H16O5
Molar mass	276.28 g/mol
Appearance	White crystalline solid
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa)
Infobox references

Lactucin is a bitter substance that forms a white crystalline solid and belongs to the group of sesquiterpene lactones. It is found in some varieties of lettuce and is an ingredient of lactucarium. It has been shown to have analgesic and sedative properties.^[1]

It acts as adenosine receptor agonist.

[edit] See also

• Lactucopicrin

[edit] References

1. ^ Wesołowska A, Nikiforuk A, Michalska K, Kisiel W, Chojnacka-Wójcik E (2006). "Analgesic and sedative activities of lactucin and some lactucin-like guaianolides in mice". J Ethnopharmacol 107 (2): 254–8. doi:10.1016/j.jep.2006.03.003. PMID 16621374. 

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