LOSC, Losc. or L.O.S.C. may refer to:

• "Losc" or "Losc Dos" a secret society formed by Tex & Merv Brown of Sydney Australia in the '50s. This has been continued on by their sons and grandsons to this day. The origins of the word L.O.S.C. is an anagram that is intensely guarded by the members.
• Lille O.S.C., the Lille Olympique Sporting Club.
• "Law of the Sea Convention" (or "Law of the Sea Conference"), an example is the United Nations Convention on the Law of the Sea.
• A common abbreviation of Cristóbal Loscos, (as in "Losc. & Pard.") in author citation of plant genus names.
• "Local On-Scene Commander" (or "Local on Scene Coordinator"), a trained and competent person who is in charge.
• "Linear Output Saturated Counter"
• "Lines of Source Code"
• "Letter of Substantial Compliance"
• "Lake Orion Soccer Club"
• "Lake Oswego Soccer Club"
• "Lake Oswego Swim Club"
• "Labour Only Sub Contracting" (or "Labour Only Sub Contractor")
• "Londonderry Occupational Safety Centre"
• "Louisiana Office of State Climatology"
• "Lackland Officers' Spouses' Club"
• "Langley Officers' Spouses' Club"
• "Lietuvos Olimpinis Sporto Centras"
• "Letter of Security Cognizance"
• "Launch Operations Support Contract"
• "Long or Short Capital" [1], a popular financial satire website.

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